MmuEX6100145 @ mm9
Exon Skipping
Gene
ENSMUSG00000057738 | Spna2
Description
spectrin alpha 2 [Source:MGI Symbol;Acc:MGI:98386]
Coordinates
chr2:29866430-29869069:+
Coord C1 exon
chr2:29866430-29866627
Coord A exon
chr2:29866706-29866852
Coord C2 exon
chr2:29868966-29869069
Length
147 bp
Sequences
Splice sites
3' ss Seq
CCTACTTGTCCACTCTGTAGCTG
3' ss Score
5.28
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
Exon sequences
Seq C1 exon
GAACACCGGACAGAAATTGATGCCAGGGCTGGCACTTTCCAGGCATTTGAGCAGTTTGGGCAGCAGCTGTTAGCTCACGGGCACTATGCCAGCCCGGAGATCAAAGAGAAACTTGATATTCTTGACCAGGAGCGCACAGACCTGGAGAAGGCCTGGGTCCAGCGCAGGATGATGCTGGACCACTGCCTGGAGTTGCAG
Seq A exon
CTGTTCCATCGGGACTGTGAACAAGCAGAAAACTGGATGGCTGCCCGGGAGGCCTTCCTAAACACAGAAGACAAAGGAGACTCGCTGGACAGTGTGGAGGCACTGATCAAAAAACATGAAGACTTTGACAAAGCTATCAATGTCCAG
Seq C2 exon
GAAGAAAAGATAGCTGCCCTGCAGGCCTTTGCCGACCAGCTCATTGCCGTTGACCACTATGCCAAGGGAGACATTGCAAACCGACGCAATGAGGTCCTTGACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057738-'41-42,'41-41,42-42=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=0.020 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(57.1=90.9),PF0043516=Spectrin=PU(2.9=4.5)
A:
PF0043516=Spectrin=FE(45.7=100)
C2:
PF0043516=Spectrin=FE(32.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCACTTTCCAGGCATTTGA
R:
GTCGGTTTGCAATGTCTCCCT
Band lengths:
254-401
Functional annotations
There are 1 annotated functions for this event
PMID: 9712874
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, cleavage reaction, glutathione s tranferase tag, western blot. ELM ID: ELMI001910; ELM sequence: DSLDS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: