RnoEX0085726 @ rn6
Exon Skipping
Gene
ENSRNOG00000015396 | Sptan1
Description
spectrin, alpha, non-erythrocytic 1 [Source:RGD Symbol;Acc:621714]
Coordinates
chr3:8579669-8582209:+
Coord C1 exon
chr3:8579669-8579866
Coord A exon
chr3:8579950-8580096
Coord C2 exon
chr3:8582106-8582209
Length
147 bp
Sequences
Splice sites
3' ss Seq
TCCACTCCTCCACTCTGTAGCTG
3' ss Score
7.26
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
GAACACCGGACAGAAATTGATGCCAGGGCTGGCACTTTCCAGGCATTTGAGCAGTTTGGGCAGCAGCTGTTGGCTCATGGGCACTATGCCAGCCCAGAGATCAAGGAGAAACTTGATATTCTTGACCAGGAGCGCACAGACCTGGAGAAGGCCTGGGTTCAGCGCAGAATGATGCTGGACCACTGCCTGGAGTTGCAG
Seq A exon
CTGTTCCATCGAGACTGTGAGCAAGCAGAGAACTGGATGGCTGCCCGGGAAGCCTTCCTAAACACAGAAGACAAAGGAGACTCGCTGGACAGTGTGGAGGCTCTGATCAAAAAACATGAAGACTTCGACAAAGCTATCAATGTCCAG
Seq C2 exon
GAGGAGAAGATAGCTGCCCTGCAGGCCTTTGCCGACCAGCTCATTGCTGTGGACCACTATGCCAAGGGAGACATTGCAAACCGACGCAATGAGGTCCTGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000015396-'59-62,'59-61,60-62
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=0.020 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(57.1=90.9),PF0043516=Spectrin=PU(2.9=4.5)
A:
PF0043516=Spectrin=FE(45.7=100)
C2:
PF0043516=Spectrin=FE(32.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCACTTTCCAGGCATTTGA
R:
GTCGGTTTGCAATGTCTCCCT
Band lengths:
254-401
Functional annotations
There are 1 annotated functions for this event
PMID: 9712874
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, cleavage reaction, glutathione s tranferase tag, western blot. ELM ID: ELMI001910; ELM sequence: DSLDS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]