Special

DmeEX0006691 @ dm6

Exon Skipping

Gene
FBgn0030503 | Tango2
Description
The gene Transport and Golgi organization 2 is referred to in FlyBase by the symbol DmelTango2 (CG11176, FBgn0030503). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:13616989..13619207. Its molecular function is described by: . It is involved in the biological process described with: Golgi organization; protein secretion. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages.
Coordinates
chrX:13617178-13618402:+
Coord C1 exon
chrX:13617178-13617575
Coord A exon
chrX:13617814-13617936
Coord C2 exon
chrX:13618273-13618402
Length
123 bp
Sequences
Splice sites
3' ss Seq
TATGTATTCCCCCATTTCAGGGA
3' ss Score
9.59
5' ss Seq
TTGGTAAAC
5' ss Score
3.22
Exon sequences
Seq C1 exon
ATTAGCTGGTCTCGCAAACAACGGATAAGACTGTATATCAGCTGTACGTACGTACGGCTATTTGGTGATAAAACCGGCGCTATAGTTCCACTGCCACAAAGTAACAAAGAGAAGACTGAGCCGAACAACCTGCCATTTTGATACCGACGCCCCACCGAGATTAAAGCCCACTTTTCCGGATCCCATTCGCAGTTGTCCCACAACCTCAAGGCACTACAAATCGCAACAATAGCCAAATAAGTATAGGATTCCGACGATGTGCGTGATATTCTTTTGTGCGGACTCGAATCCGCAACCGGGTGGCTACAAGCTCATCCTGGCCTCCAATCGGGACGAGTTCTTTGCCCGCGCCACCCTATCGGCAGCCAAGTGGGCGAATGCCGATCATGTTTACGGAG
Seq A exon
GGATCGATCTGGAGCCGGGACGCGAGGGCGGCACCTGGCTGGCGATCGGCCACTCCGCTGGCTTCTTTAAGGTGGGCGCCCTGCTCAATCTGACCGGCGAGCCCAAGCCACGCGATGCAGTTG
Seq C2 exon
GGCGCGGCATGATTGTGGCGGACTATGTTACCCGGGCGGACGAGGAGCACAGCATCCTGAACTACAACGAAAGGCTGCTCAAAGATTGCACCAAGTATTCTGCCTTCAACTTTGTGTCCATCGAAATTGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0030503-'5-6,'5-4,8-6
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.048 C2=0.223
Domain overlap (PFAM):

C1:
PF057427=NRDE=PU(46.1=97.9)
A:
PF057427=NRDE=FE(14.8=100)
C2:
PF057427=NRDE=FE(15.5=100)


Main Inclusion Isoform:
FBpp0073638


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0300867, FBpp0304111, FBpp0309341


Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTCCGGATCCCATTCGCAG
R:
ATAGTCCGCCACAATCATGCC
Band lengths:
253-376
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)