DmeEX6007774 @ dm6

Exon Skipping

Gene

Description

The gene lethal (2) 37Cd is referred to in FlyBase by the symbol Dmell(2)37Cd (CG10563, FBgn0086445). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:19127260..19129326. Its molecular function is unknown. It is involved in the biological process described with: transcription initiation from RNA polymerase III promoter. 21 alleles are reported. The phenotypes of these alleles manifest in: adult abdomen; macrochaeta; melanotic mass; wing. The phenotypic classes of alleles include: increased mortality; lethal - all die before end of pupal stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Coordinates

chr2L:19127260-19127843:+

Coord C1 exon

chr2L:19127260-19127392

Coord A exon

chr2L:19127455-19127656

Coord C2 exon

chr2L:19127714-19127843

Length

202 bp

Sequences

Splice sites

3' ss Seq

ATATCTTATTCCATGCACAGGTT

3' ss Score

7.51

5' ss Seq

AAAGTGAGT

5' ss Score

8.4

Exon sequences

Seq C1 exon

TCAGTTTCATATCATGTCGCGCCAATTGAGTTTCAATCCGCAGAAAGAATATGAGTTGATCGAGTACCCCGGCCGAGTGGTAAATCCCGATCGGATGATAGCCACTCTGGGCGGCATCATCAATGTGTCTAAG

Seq A exon

GTTTTGGGCGACGAAGTGAAACGATTGGCGTTGCACTTCCATCCGGAGAATCCCTACAACAAACCCACTTTTGGGGACTGCACGGATAAGACTGGTGTCCTGCTATCCATAACCGTGAGGCGCCACAAAAAGGACAAGCAACGGCCTCCGGAATATTTTGTGCGGGTGTTGGGCCACTGCAGCAGGAGCTTCACCTTTGAAA

Seq C2 exon

CGCTTTGTGATTTCCAATACCTACCCCTCTGGTCAACTCCCAAAAGTGACAACGCAAATGCTGCCCAGGAGCTCACGTACGCTTTGGACCAGTTGAAACCCAAAAACACCACCGACTTGGACTACTTTAA

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0086445-'1-1,'1-0,2-1=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion