DmeEX6009131 @ dm6
Exon Skipping
Gene
FBgn0033309 | CG8735
Description
The gene Lunapark is referred to in FlyBase by the symbol DmelLnpk (CG8735, FBgn0033309). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:8596972..8599962. Its molecular function is unknown. It is involved in the biological process described with: endoplasmic reticulum tubular network organization. 8 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval brain. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:8599271-8599858:-
Coord C1 exon
chr2R:8599811-8599858
Coord A exon
chr2R:8599472-8599701
Coord C2 exon
chr2R:8599271-8599403
Length
230 bp
Sequences
Splice sites
3' ss Seq
ATTCGCGAATCTAATTATAGAAA
3' ss Score
3.96
5' ss Seq
TGTGTGAGT
5' ss Score
5.84
Exon sequences
Seq C1 exon
TTAAATTGCGGATCATACACCATGGGATTTGTGTTATCCAAGCTGCGG
Seq A exon
AAAGAAAAGTCCACGGAGGCGGTGTTGGAGGGGCTGCAGACGCAGATCCAAGCGTTGGAGAAGTACATGATCAACACCGAGGAGCGCAAGCGCCGGTTCGTGACGAACTTCGTGGGCTTCACCATCGGAGCATATATCGTGGGCTTCGGGCTCTGGTGGTACTTCTACTTCCCGCCGACCATGCAGGAGTGCTTCATGTACCTGGTACCGCTGCTGCTATTCCCCATTGT
Seq C2 exon
CATCATCTTTCTGCGGCGGCTGTTTACGTGGTACTTCCAGCGCAAGCTCAACAAAAATGGCGATAAGCTGACTCGTCTGAAGGAGGACAAGCGCAAGATATTGGAGCAGGTCATGGACAAAGAGACCTATAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033309-'2-2,'2-1,5-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF074317=DUF1512=PU(20.0=19.5),PF148581=DUF4486=PU(9.8=13.0)
C2:
PF074317=DUF1512=FE(58.7=100),PF148581=DUF4486=FE(43.1=100)
Main Inclusion Isoform:
FBpp0087809
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0308451
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TAAATTGCGGATCATACACCATGGG
R:
CTTATAGGTCTCTTTGTCCATGACCT
Band lengths:
180-410
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)