DmeEX6014799 @ dm6
Exon Skipping
Gene
FBgn0035581 | CG17150
Description
The gene dynein, axonemal, heavy chain 3 is referred to in FlyBase by the symbol DmelDnah3 (CG17150, FBgn0035581). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:4861269..4895749. Its molecular function is described by: dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein light intermediate chain binding; ATP binding. It is involved in the biological process described with: cilium movement; response to auditory stimulus; microtubule-based movement; sperm competition. 17 alleles are reported. The phenotype of these alleles manifest in: spermatozoon. The phenotypic classes of alleles include: fertile; pain response defective; auditory perception defective; viable; male sterile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in adult male stages.
Coordinates
chr3L:4873080-4873908:+
Coord C1 exon
chr3L:4873080-4873184
Coord A exon
chr3L:4873248-4873418
Coord C2 exon
chr3L:4873761-4873908
Length
171 bp
Sequences
Splice sites
3' ss Seq
GACTTACGTTTGTTTCCTAGGGA
3' ss Score
9
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
Exon sequences
Seq C1 exon
ATTGGCAGTCTGACCTTTGACGATAACATGGAGATCGTGGAGATGGTCAGTGATGAGGAGGAGCGTGTGGCCCTGGTGCGGAAAATTAACCCGCAGTTGGCCAAT
Seq A exon
GGATTAGTGGAGATGTGGCTTAAGGAGGTGGAGATGGTGATGCTGGACAGCGTGAAGGAGCAGATGCGCGAGGCCTGGGAGGACTACGCCATGGTGGAGCGCATCTCCTGGGTGGTCAGTTGGCCCGGTCAGGTGGTGCAGGGCATCTCCTGCATGGCCTGGACCTACGAG
Seq C2 exon
GTGGAGGAGGCCATCGAGACGAAGGAGCTGCCGGCTTATTTGGAGAAGTCCAATCTGCAGATTGCCGACCTGGTGCAATTGGTGCGCACGGATCTGCAAGCCGGAGTCCGGATTGCTGTGGAGGCGCTGATTGTCCTGGATGTTCATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035581-'22-21,'22-20,23-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF083938=DHC_N2=FE(8.2=100)
A:
PF083938=DHC_N2=PD(7.0=50.9)
C2:
NO
Main Inclusion Isoform:
FBpp0288420

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGCAGTCTGACCTTTGACG
R:
AACATCCAGGACAATCAGCGC
Band lengths:
248-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)