DmeEX6024580 @ dm6
Exon Skipping
Gene
FBgn0051005 | qless
Description
The gene qless is referred to in FlyBase by the symbol Dmelqless (CG31005, FBgn0051005). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:31236035..31252608. Its molecular function is described by: trans-hexaprenyltranstransferase activity; prenyltransferase activity. It is involved in the biological process described with: response to mitochondrial depolarisation; ubiquinone biosynthetic process; neuroblast development; isoprenoid biosynthetic process; negative regulation of apoptotic process. 16 alleles are reported. The phenotype of these alleles manifest in: larval neuroblast. The phenotypic classes of alleles include: locomotor behavior defective; cell death defective; phenotype; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages.
Coordinates
chr3R:31241635-31242774:-
Coord C1 exon
chr3R:31242598-31242774
Coord A exon
chr3R:31242171-31242310
Coord C2 exon
chr3R:31241635-31241776
Length
140 bp
Sequences
Splice sites
3' ss Seq
CCTTTCGAATCTTCTTTCAGCTG
3' ss Score
9.51
5' ss Seq
ACAGTGAGT
5' ss Score
8.34
Exon sequences
Seq C1 exon
CAAAGTCCCCACAAGTGCAGCCAATCGCTGCAGTACTCGCAAAGTTCCAAGGCGAATCTGAGGCAGCACAGCTCGGTCCACACACAACAGCCAGCAGGTCCTGTGAGGGAGTTCCAGATCGATCCCTACATCATACTCGATGACGACCTCAAGTACTTCTACGACGATGTGCGATAT
Seq A exon
CTGCTGAAATCGGGCACATCCCAGCCAGAGTTGGACACCATTGCCAGCTATTACTTCGATGGCCAGGGCAAGGCTCTGCGACCCATGGTTACCATGCTGATGGCCAAGGCGATAAACTATCACCTGAACAACGAGTCACA
Seq C2 exon
CCAATTAGTACACAAACAGCGACAGATCGCCCTCTTTTCGGAGATGGTGCACTCGGCCAGTCTGGTCCACGACGATGTCATCGATCAGTCGGACTTCCGACGCGGCAAGCCCAGCGTGAATGCTCTGTGGAACCACAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0051005-'3-2,'3-1,4-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.271 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0034812=polyprenyl_synt=PU(13.7=76.6)
C2:
PF0034812=polyprenyl_synt=FE(17.9=100)
Main Inclusion Isoform:
FBpp0085131

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0311406
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GAATCTGAGGCAGCACAGCTC
R:
TTCCACAGAGCATTCACGCTG
Band lengths:
256-396
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)