DreEX0010942 @ danRer10
Exon Skipping
Gene
ENSDARG00000071090 | actn2b
Description
actinin, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-051127-39]
Coordinates
chr17:20102567-20106850:-
Coord C1 exon
chr17:20106704-20106850
Coord A exon
chr17:20105637-20105702
Coord C2 exon
chr17:20102567-20102725
Length
66 bp
Sequences
Splice sites
3' ss Seq
CTTTAATATTTGCCATGCAGAAG
3' ss Score
5.38
5' ss Seq
CTGGTAGGG
5' ss Score
6.35
Exon sequences
Seq C1 exon
CATGTTCGCGTTGGCTGGGAGCTCCTATTGACCACGATTGCTCGCACAATTAATGAAATCGAGACTCAAATTTTGACCCGTGATGCAAAAGGGATCAGCCAGGAGCAGATGCATGAGTTCCGGTCCTCTTTCAACCATTTTGATCGG
Seq A exon
AAGAAGAACGGGGGCATGGATTCTGATGACTTTAGGGCCTGTCTGATCTCGATGGGTTATGATCTG
Seq C2 exon
GGAGAGGTGGAGTTTGCTCGGATCATGATGCTGGTGGATCCAAATGCTTCAGGCAATGTGTCGTTCCAGTCCTTCATTGATTTCATGACTAGAGAGACAGCAGACACAGACACAGCTGAACAGGTCATTGCTTCCTTCAAGATCCTCGCTGCAGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000071090_MULTIEX1-3/3=C1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.034 A=0.045 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(20.2=42.9),PF088696=XisI=PD(31.8=42.9),PF134051=EF-hand_6=PU(33.3=20.4)
A:
PF138331=EF-hand_8=PU(37.7=90.9)
C2:
PF138331=EF-hand_8=PD(58.5=58.5),PF087265=EFhand_Ca_insen=PU(26.9=34.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGCTGGGAGCTCCTATTGA
R:
CCACCAGCATCATGATCCGAG
Band lengths:
174-240
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]