DreEX6023030 @ danRer10
Exon Skipping
Gene
ENSDARG00000018032 | scn8ab
Description
sodium channel, voltage gated, type VIII, alpha subunit b [Source:ZFIN;Acc:ZDB-GENE-060906-2]
Coordinates
chr6:39431435-39441235:-
Coord C1 exon
chr6:39440960-39441235
Coord A exon
chr6:39435798-39436091
Coord C2 exon
chr6:39431435-39431567
Length
294 bp
Sequences
Splice sites
3' ss Seq
CTTTTTTTTTCTACCCCCAGTCG
3' ss Score
10.14
5' ss Seq
GAGGTGAAA
5' ss Score
2.91
Exon sequences
Seq C1 exon
GCCAATGCCATGGCGACTTCAGCAGGTACAGTGTCTGAGGACGCAGTGGAGGACGATGGCGGAGGGCATCTGTCCCGCAGCTCCTCTGAAGTGTCCAAACTGAGCTCCAAGAGCGCCAAGGAGCGCAGGAACAGAAAGAAGAAGTGGAGGAAAGAGCAGGAGGAGAAGGGAGACAGTGAGAAAGTAGTGAAGTCAGAATCTGATGATGGCAGCAAGAGGAGCCGCTTCCGTTTCAGAGACAACAGGCTTGGGCGGAAGGCCTCCATCATGAATCAG
Seq A exon
TCGCTGTTGAGCATCCCTGGCTCGCCCTTCATGTCGCGCCGCAGCAGTATATTCAGCTTCAAGGGCTCAGAGAACGAGTTTGCAGACGATGAGCACAGCACGGTGGAGGAGAGCGAGGATCGCCGTGGCTCTCTCTTCGTCCCATACAGACGCAGCAGCTACAGCGGCTACAGTCAGGGCTCTTCTCGAATTAACCCGCTGGCTCCACACCCAGGCTGCAAGAGAAACAGCACGGTGGACTGCAATGGCGTGGTGTCTCTGATCGGGCCTGGACCTGGCCGACTACTGCCTGAG
Seq C2 exon
ACAACAGAGGTAGAGGGGAAGAGGAAACACTCAGGTTCTCTTATGGTGTCCGTGGATCAGCTCAATACGTCCTTTAGCCGGAAAGAGCGAGCAAACAGTGCAATGACTGTTGTCACCAACACACTTGTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000018032-'15-13,'15-12,16-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.935 A=0.459 C2=0.133
Domain overlap (PFAM):
C1:
PF0043013=ATP-synt_B=PD(46.7=60.9),PF0310514=SPX=FE(46.9=100),PF119333=DUF3451=PU(31.7=68.5)
A:
PF0310514=SPX=PD(32.0=63.3),PF119333=DUF3451=FE(48.7=100)
C2:
PF119333=DUF3451=PD(18.1=80.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGACTTCAGCAGGTACAGTG
R:
CCTGAGTGTTTCCTCTTCCCC
Band lengths:
299-593
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]