DreEX6083478 @ danRer10
Exon Skipping
Gene
ENSDARG00000019231 | spna2
Description
spectrin alpha 2 [Source:ZFIN;Acc:ZDB-GENE-051113-60]
Coordinates
chr21:13098489-13099919:+
Coord C1 exon
chr21:13098489-13098593
Coord A exon
chr21:13098687-13098895
Coord C2 exon
chr21:13099799-13099919
Length
209 bp
Sequences
Splice sites
3' ss Seq
CGTTGTCTTTGTTCTTGCAGGAT
3' ss Score
12.06
5' ss Seq
TAAGTATGC
5' ss Score
2.72
Exon sequences
Seq C1 exon
GTTGAGGCTCTTCTTGCCTCTGAGGATTATGGGAAAGATCTGGCTTCAGTCAACAATCTGCTGAAGAAGCACCAGCTGTTGGAGGCTGATATCTCTGCTCATGAG
Seq A exon
GATCGTTTGAAGGATCTTAATGGCCAGGCTGACAGTCTGATGGCCAGCAACGCTTTCGACACATCTCAGGTCAAAGACAAGCGGGATGCCGTTAACGGACGCTTCGGCAAAATCAAGAGCATGGCAGCGGGACGGCGAGCCAAGCTGAACGAATCGCATCGTCTGCACCAGTTCTTCAGGGATCTGGACGATGAGGAGTCCTGGATTAA
Seq C2 exon
GGAAAAGAAGTTGTTGGTGAGCTCGGAGGACTACGGACGTGATTTGACAGGGGTGCAGAATCTGAGGAAGAAGCACAAGAGGCTGGAGGCTGAGCTGGGAGCACACGAGCCGGCCATTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000019231-'50-57,'50-56,51-57=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.086 C2=0.171
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=FE(32.4=100)
A:
PF0043516=Spectrin=PD(47.6=71.4),PF0043516=Spectrin=PU(16.2=24.3)
C2:
PF0043516=Spectrin=FE(38.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTCTTCTTGCCTCTGAGGA
R:
CTGAATGGCCGGCTCGTG
Band lengths:
221-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]