DreEX6095574 @ danRer10
Exon Skipping
Gene
ENSDARG00000057169 | abca4a
Description
ATP-binding cassette, sub-family A (ABC1), member 4a [Source:ZFIN;Acc:ZDB-GENE-050517-3]
Coordinates
chr24:28484491-28490835:+
Coord C1 exon
chr24:28484491-28484632
Coord A exon
chr24:28484710-28484849
Coord C2 exon
chr24:28490708-28490835
Length
140 bp
Sequences
Splice sites
3' ss Seq
AATGCATTCCTCTTGCTCAGATT
3' ss Score
6.86
5' ss Seq
CAGGTCAGC
5' ss Score
7.16
Exon sequences
Seq C1 exon
GTCATTTTCCAAACAAAGCTATGCCCTCATCTGGCGTCCTTCCATGGATCCAGGGGATCGTCTGCAATGCCAACAACCCCTGTTTCCAGCACACGACTCGTGGAGAATCTCCAGGCCTGGTGTCCAACTACAACAACTCAAT
Seq A exon
ATTGGCTCGTTTTTGGTCAGACGCACAGGAGCTGCTGTTTGAAGATACCGAGTTTCTGCAGTTGGGACGGTTATGGCAGGAACTTATGGCTATGAGCAGCTTTATGGATACTCTTCGGACCAATCCTGAGGCAATTGCAG
Seq C2 exon
GTCGAGGCATAAAAGTGGAAGACATTTTAAAGGATGACGAAACTCTCACAGCATACCTGCTCAGAGATGTTCCTCTCACTGAATCTGTGGTACAACAGCTGATCAACTCACAGATTCGACCCGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057169-'3-6,'3-5,4-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.021 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCATCTGGCGTCCTTCCATG
R:
CTCGGGTCGAATCTGTGAGTTG
Band lengths:
242-382
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000561; ELM sequence: YNNSIL; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]