HsaEX0002604 @ hg38
Exon Skipping
Gene
ENSG00000143382 | ADAMTSL4
Description
ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706]
Coordinates
chr1:150556162-150557050:+
Coord C1 exon
chr1:150556162-150556366
Coord A exon
chr1:150556691-150556793
Coord C2 exon
chr1:150556939-150557050
Length
103 bp
Sequences
Splice sites
3' ss Seq
GATCCCCCTGGGTCCTACAGGGC
3' ss Score
7.32
5' ss Seq
TATGTGAGC
5' ss Score
2.97
Exon sequences
Seq C1 exon
AGCCCCGGCTGTGATGGGATCCTTGGCTCTGGCAGGCGTCCTGATGGCTGTGGAGTCTGTGGGGGTGATGATTCTACCTGTCGCCTTGTTTCGGGGAACCTCACTGACCGAGGGGGCCCCCTGGGCTATCAGAAGATCTTGTGGATTCCAGCGGGAGCCTTGCGGCTCCAGATTGCCCAGCTCCGGCCTAGCTCCAACTACCTGG
Seq A exon
GGCCGGCGGGACCGTCTTTCGATATAACCGTCCTCCCAGGGAGGAGGGCAAAGGGGAGAGTCTGTCGGCTGAAGGCCCCACCACCCAGCCTGTGGATGTCTAT
Seq C2 exon
ATGATCTTTCAGGAGGAAAACCCAGGCGTTTTTTATCAGTATGTCATCTCTTCACCTCCTCCAATCCTTGAGAACCCCACCCCAGAGCCCCCTGTCCCCCAGCTTCAGCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143382-'17-28,'17-27,18-28
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.603 C2=0.447
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=PU(35.3=59.4)
A:
PF059869=ADAM_spacer1=FE(49.1=100)
C2:
PF059869=ADAM_spacer1=PD(13.8=42.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGATGGCTGTGGAGTCTGTG
R:
GGTGGGGTTCTCAAGGATTGG
Band lengths:
246-349
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development