HsaEX0012349 @ hg19
Exon Skipping
Gene
ENSG00000137225 | CAPN11
Description
calpain 11 [Source:HGNC Symbol;Acc:1478]
Coordinates
chr6:44148989-44150972:+
Coord C1 exon
chr6:44148989-44149057
Coord A exon
chr6:44150678-44150756
Coord C2 exon
chr6:44150856-44150972
Length
79 bp
Sequences
Splice sites
3' ss Seq
ATATCTGTCTGTCTCTTCAGGAC
3' ss Score
12.22
5' ss Seq
CAGGTGGCC
5' ss Score
3.48
Exon sequences
Seq C1 exon
AAAGATGGCTCTGGCAAGCTGGGGCTTCTAGAGTTCAAGATCCTGTGGAAAAAACTCAAGAAATGGATG
Seq A exon
GACATCTTCAGAGAGTGTGACCAGGACCATTCAGGCACCTTGAACTCCTATGAGATGCGCCTGGTTATTGAGAAAGCAG
Seq C2 exon
GCATCAAGCTGAACAACAAGGTAATGCAGGTCCTGGTGGCCAGGTATGCAGATGATGACCTGATCATAGACTTTGACAGCTTCATCAGCTGTTTCCTGAGGCTAAAGACCATGTTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137225_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138331=EF-hand_8=PD(29.5=78.3),PF134991=EF-hand_7=PU(5.3=21.7)
A:
PF134991=EF-hand_7=FE(27.4=100)
C2:
PF134991=EF-hand_7=FE(41.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGATGGCTCTGGCAAGCTG
R:
AGCCTCAGGAAACAGCTGATG
Band lengths:
172-251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)