HsaEX0012349 @ hg38
Exon Skipping
Gene
ENSG00000137225 | CAPN11
Description
calpain 11 [Source:HGNC Symbol;Acc:HGNC:1478]
Coordinates
chr6:44181252-44183235:+
Coord C1 exon
chr6:44181252-44181320
Coord A exon
chr6:44182941-44183019
Coord C2 exon
chr6:44183119-44183235
Length
79 bp
Sequences
Splice sites
3' ss Seq
ATATCTGTCTGTCTCTTCAGGAC
3' ss Score
12.22
5' ss Seq
CAGGTGGCC
5' ss Score
3.48
Exon sequences
Seq C1 exon
AAAGATGGCTCTGGCAAGCTGGGGCTTCTAGAGTTCAAGATCCTGTGGAAAAAACTCAAGAAATGGATG
Seq A exon
GACATCTTCAGAGAGTGTGACCAGGACCATTCAGGCACCTTGAACTCCTATGAGATGCGCCTGGTTATTGAGAAAGCAG
Seq C2 exon
GCATCAAGCTGAACAACAAGGTAATGCAGGTCCTGGTGGCCAGGTATGCAGATGATGACCTGATCATAGACTTTGACAGCTTCATCAGCTGTTTCCTGAGGCTAAAGACCATGTTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137225_CASSETTE4
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138331=EF-hand_8=PD(29.5=78.3),PF134991=EF-hand_7=PU(5.3=21.7)
A:
PF134991=EF-hand_7=FE(27.4=100)
C2:
PF134991=EF-hand_7=PD(48.4=77.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGATGGCTCTGGCAAGCTG
R:
AGCCTCAGGAAACAGCTGATG
Band lengths:
172-251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development