HsaEX0015312 @ hg19
Exon Skipping
Gene
ENSG00000169684 | CHRNA5
Description
cholinergic receptor, nicotinic, alpha 5 (neuronal) [Source:HGNC Symbol;Acc:1959]
Coordinates
chr15:78857862-78879031:+
Coord C1 exon
chr15:78857862-78858167
Coord A exon
chr15:78873153-78873304
Coord C2 exon
chr15:78878987-78879031
Length
152 bp
Sequences
Splice sites
3' ss Seq
TTTAAAAATTTGTTATACAGGAT
3' ss Score
6.69
5' ss Seq
GTGGTAGGT
5' ss Score
7.23
Exon sequences
Seq C1 exon
ACATGCGTCCCGAGCCCGCCAGAAGCTGCTAGGCTGAGGCTGCTGTCCCGGCGGGAGCTGTGGCGCGGAGCGGCCCCTCTGCTGCGTCTGCCCTCGTTTTGTCTCACGACTCACACTCAGTGCTCCATTCCCCAAGAGTTCGCGTTCCCCGCGCGGCGGTCGAGAGGCGGCTGCCCGCGGTCCCGCGCGGGCGCGGGGCGATGGCGGCGCGGGGGTCAGGGCCCCGCGCGCTCCGCCTGCTGCTCTTGGTCCAGCTGGTCGCGGGGCGCTGCGGTCTAGCGGGCGCGGCGGGCGGCGCGCAGAGAG
Seq A exon
GATTATCTGAACCTTCTTCTATTGCAAAACATGAAGATAGTTTGCTTAAGGATTTATTTCAAGACTACGAAAGATGGGTTCGTCCTGTGGAACACCTGAATGACAAAATAAAAATAAAATTTGGACTTGCAATATCTCAATTGGTGGATGTG
Seq C2 exon
GATGAGAAAAATCAGTTAATGACAACAAACGTCTGGTTGAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169684_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.035 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0293118=Neur_chan_LBD=PU(19.1=76.5)
C2:
PF0293118=Neur_chan_LBD=FE(12.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCGTTTTGTCTCACGACT
R:
TCAACCAGACGTTTGTTGTCA
Band lengths:
256-408
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)