HsaEX0037152 @ hg19

Exon Skipping

Gene

ENSG00000127603 | MACF1

Description

microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:13664]

Coordinates

chr1:39852859-39888572:+

Coord C1 exon

chr1:39852859-39854330

Coord A exon

chr1:39888046-39888207

Coord C2 exon

chr1:39888402-39888572

Length

162 bp

Sequences

Splice sites

3' ss Seq

TTTGGCTTGTAATTATCTAGATG

3' ss Score

6.01

5' ss Seq

AAGGTGAGT

5' ss Score

10.47

Exon sequences

Seq C1 exon

GAGTGAACAGTGGTTGTGTGATGATGGAAAACAAGCTGGAGGGGATTGGCCAGTTTCACTGCCGGGTCCGAGAGATGTTCTCTCAATTGGCAGACCTGGATGATGAGCTAGATGGCATGGGTGCTATTGGCAGAGACACTGATAGCCTCCAGTCCCAAATCGAGGATGTCCGGCTATTCCTTAACAAAATTCACGTCCTCAAATTAGACATAGAGGCCTCTGAAGCAGAGTGTCGACATATGCTAGAAGAAGAGGGGACTCTGGATTTGTTAGGTCTCAAAAGGGAGCTAGAAGCCCTGAACAAACAGTGTGGCAAACTGACAGAGAGGGGGAAAGCTCGTCAGGAACAGCTGGAACTGACACTAGGCCGTGTAGAGGACTTCTACAGGAAATTGAAAGGACTCAATGACGCGACCACAGCAGCAGAGGAGGCAGAGGCCCTCCAGTGGGTAGTGGGGACCGAAGTGGAAATCATCAACCAACAATTAGCAGATTTTAAA

Seq A exon

ATGTTTCAGAAAGAACAAGTGGATCCTCTTCAGATGAAATTGCAGCAGGTGAATGGACTTGGCCAGGGATTAATTCAGAGTGCAGGAAAAGACTGTGATGTACAGGGTTTAGAACATGACATGGAAGAGATCAATGCTCGATGGAATACATTGAATAAAAAG

Seq C2 exon

GTCGCACAAAGAATTGCACAGCTACAGGAAGCTTTGTTGCATTGTGGGAAGTTTCAAGATGCCTTGGAGCCATTGCTCAGCTGGTTGGCAGATACCGAGGAGCTCATAGCCAATCAGAAACCTCCATCTGCTGAGTATAAAGTGGTGAAAGCACAGATCCAAGAACAGAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000127603-'84-85,'84-84,86-85

Average complexity

C1

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=0.096 A=0.018 C2=0.018

Domain overlap (PFAM):

C1:

PF0043516=Spectrin=PD(8.3=1.8),PF0043516=Spectrin=WD(100=22.0),PF0043516=Spectrin=WD(100=21.3),PF0043516=Spectrin=WD(100=21.3),PF0043516=Spectrin=PU(39.8=8.7)

A:

PF0043516=Spectrin=FE(49.1=100)

C2:

PF0043516=Spectrin=PD(10.2=15.8),PF0043516=Spectrin=PU(41.1=77.2)

Main Inclusion Isoform:

ENSP00000455823