HsaEX0037160 @ hg19
Exon Skipping
Gene
ENSG00000127603 | MACF1
Description
microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:13664]
Coordinates
chr1:39715686-39720320:+
Coord C1 exon
chr1:39715686-39715775
Coord A exon
chr1:39717518-39717613
Coord C2 exon
chr1:39719970-39720320
Length
96 bp
Sequences
Splice sites
3' ss Seq
GCCTTGGTTGGTGGCCAAAGGAG
3' ss Score
0.53
5' ss Seq
GTAGTAGGT
5' ss Score
2.71
Exon sequences
Seq C1 exon
GTCCGCAAGCACATCAATGATCTTTATGAAGATCTGCGGGATGGCCATAACCTGATCTCTCTGTTGGAGGTCCTCTCAGGCATCAAACTG
Seq A exon
GAGCCAGCAGGGCTGAAGACCCTCCGTCTGGTGAGCATGCCCTCCTGGTGCCATACAAACAACGAGGAGCAGGCGGAGGAAGATGATGATGATGTA
Seq C2 exon
CCCCGGGAGAAGGGCAGGATGCGTTTTCATAGGCTGCAGAATGTGCAGATTGCCCTGGACTTCCTAAAGCAGCGACAGGTAAGACCATCACATGCCTTCCCCATTCTTCCAGGCTGTGTTGGCATTGGGGCCCTATTCAGAGATGTTTTTAGTGCCCCTAGTAAGCTCTCAGTAAATGCTAAATCTGATTGACCCAGTTCTGAGTCTTAACTTGCTAGTGAGCAATTGTATTCTGGTTAGAGAAATCATTCAGTACTCACACAGAACTTGTGACCTCCTTGAGAGGAAGAATGTTCACGGAGAAGAACATGATGATAAAGATGGAATTTTGTGGATGCACCTTAGGTGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000127603_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.438 C2=0.022
Domain overlap (PFAM):
C1:
PF0030726=CH=FE(28.7=100)
A:
PF0030726=CH=FE(23.3=100)
C2:
PF0030726=CH=FE(24.8=100)
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATCTGCGGGATGGCCATAAC
R:
GCCAACACAGCCTGGAAGAAT
Band lengths:
183-279
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)