HsaEX0038733 @ hg19
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66198423-66206311:-
Coord C1 exon
chr15:66206075-66206311
Coord A exon
chr15:66204420-66204538
Coord C2 exon
chr15:66198423-66198479
Length
119 bp
Sequences
Splice sites
3' ss Seq
GCACCTTGTTCTCTTCCCAGATT
3' ss Score
8.98
5' ss Seq
AAGGTACCG
5' ss Score
9.67
Exon sequences
Seq C1 exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
Seq A exon
ATTTGTCTCAAAGTAGCAGCCATGCCCACTGCTTTTCCAATTCCAGCTACCACGCACTGGCATGTGGGGGGCCTGCCACCAGCCAGGCCAGCACTCTGGACAGGAACAGCCCCACCAAG
Seq C2 exon
GTGCTTGTGGAATGGATAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890_MULTIEX1-1/5=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.053 A=0.100 C2=0.050
Domain overlap (PFAM):
C1:
PF153301=SIT=PU(91.4=68.8),PF055456=FixQ=WD(100=46.8),PF117433=DUF3301=PU(87.3=62.3)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATGGAGGAGCTGAATCCCT
R:
ACGTCTATCCATTCCACAAGCAC
Band lengths:
251-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)