HsaEX0038733 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65906085-65913973:-
Coord C1 exon
chr15:65913737-65913973
Coord A exon
chr15:65912082-65912200
Coord C2 exon
chr15:65906085-65906141
Length
119 bp
Sequences
Splice sites
3' ss Seq
GCACCTTGTTCTCTTCCCAGATT
3' ss Score
8.98
5' ss Seq
AAGGTACCG
5' ss Score
9.67
Exon sequences
Seq C1 exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
Seq A exon
ATTTGTCTCAAAGTAGCAGCCATGCCCACTGCTTTTCCAATTCCAGCTACCACGCACTGGCATGTGGGGGGCCTGCCACCAGCCAGGCCAGCACTCTGGACAGGAACAGCCCCACCAAG
Seq C2 exon
GTGCTTGTGGAATGGATAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890_MULTIEX1-1/5=C1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.071 A=0.325 C2=0.142
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(18.9=8.8)
A:
NO
C2:
NO
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATGGAGGAGCTGAATCCCT
R:
ACGTCTATCCATTCCACAAGCAC
Band lengths:
251-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development