HsaINT0101803 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65906085-65913973:-
Coord C1 exon
chr15:65913737-65913973
Coord A exon
chr15:65906142-65913736
Coord C2 exon
chr15:65906085-65906141
Length
7595 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
TACATGTTATTTTTACACAGGTG
3' ss Score
7.97
Exon sequences
Seq C1 exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
Seq A exon
GTAAGGGCCATGCTCCTGGCCTCCCTCCTCTTCCCCTCCACACACACATACCCCAGGAATGGTTGTGCCTGTAGGGTTGGCTGCTGTGGCTGAATGTGGAAGCTCAGTCTCCCCTAGAGTGACAGTGGGGATGGGGAGCAGGAGCCTACCTAGAGAAGATATCTGGGGTTCCAAGGGAAAATTGTTTCCTGAGTCCCTAGCTCTGAGCAGCTGTGGTTGGGAGCCTCCTGCCATTTTCCCAGAGCTTCCCTATCCTTCTCACCAGCCTTCGGCCTCAGGAGCACCCACACTAACCAGTCACTTTCCTAAGCTCTCCAGAGGACTGTCTCCCCAACCTGATGCCTGTACCACCTCAGGAGGCTAGACCTTGGAGCCCAGTGCCCAGAGCTCATCCATTTCTGTTTCCCTGGTGAACGCCTCAGGACAACCCTCCTTCCCAGTTCCCAGTTAGGAGGGTCCTATTAGTACAGCGGAAGGGGACAGTACCTGACTTGGGAGGTCTGAAAGTTTGGACAATGTCCCTCTGGCAAGTGTGCCAGAGCCCAGTGCATCCATGAATGTGGTTAACAGCTCCAATAGGCATTTTATTTGGGAGTCTGAGTGGGGTCAAGATGGGGCTGCTGGGCGATATCCTTCCTTTCCCCTGAACCCTGGACTGCTGCCTTGGAAATACGAAAGGTTTTTTGCTTCATATTGGCTAAACAGTAGAGGCCAAAATGCTCTGAAATTGCCCTATAGTCCTGGGCTATGTGAGGCTGAGCCTGTCTGGGTGAGCACAAGGTGACAGCTCTCTCCAGGTAGCTCCATGGCACGTGGCTCATGGCTCATCTGCAGCCTCCTGCATCTTGTGCTTAGAAAACCCAGATCACTTCAGCCCATTCCTGCTAAGTGTTGCCTTCTGTATGTCCAGCTTCATGCTAGGCACTGCAGGATAGACAGAGGCAGGCCAGTGCACACCATGCCTTCAAGGAGCTCCTGGTCTACATGCCACACTACAGCCAAAGCAGACATCCCACACACAGATTTGGGGATTTTCTTCTATGACTATACTGAGAAGGCTGGCTAGGGTTTCCTATGCCATTCCTCTGGTATTCCCCAGCCCTATGGAGAGGTTCTGGAATCCTTAGGAGGGAAGAGCAGAGTCAGAAGTGAGGTTCTCTTTATGATCTCATTACCAGGATGTGACCCTAGAAGGAAGCAGGTGAGTCCAGCCCTAAATAGGGACTCAGGGACATGTAAGGCTATCAAAGCAAACATGCCCCATCCAGGCTCCAGTTGATAGTGCCTCCCCTTGGCACAGGTGAGCCTATCCTGCATTCTGCATGCTGCAGGGAGGACCAGCGTAAGGGAAGGAGCAAATCAGGCTCTCCAGATTTCAGTAGGAGTAGTGGATGCCAGGAAGCTTGGGGGATGGGGTACTTGCCTGTTTGTCTTTGCAGGGCTCTCTCAAGGCTCCCAGCGCAAGCATTAGTACTGGGGGTATCTCATGCCAGGGGCAGGGGTATGATGGTATGTGGCACCTTGTTCTCTTCCCAGATTTGTCTCAAAGTAGCAGCCATGCCCACTGCTTTTCCAATTCCAGCTACCACGCACTGGCATGTGGGGGGCCTGCCACCAGCCAGGCCAGCACTCTGGACAGGAACAGCCCCACCAAGGTACCGGGCCCCTGATTCCCCAGCCCCCACTCACTGCCCTCTCATTTAACCCTCACCTCTGCCCAGGAAGGAACTGCACGCCCCCCGCCACATGGAGGGTCCATGTAGAACTGACCACCAATACATTAAAAGCAACCTTGCAATCCGTGGTACACGTAAACACTCTGTGAGGCATGTAATGGAGCCAGCATGTTATGTGGAGTGCCGTGTAACCAACCCACAGCATCACTCAGTATAACATATACCCCTGTACCCTGTGTGTAACCAACTGGTACCAAGTCATGTAATCATGTATTTGCTTTATCACCTATAATCATGTAGACACTTTTGCCACATGTCAACACGTAATCAAAACACTAGACCACCTTGTAGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACAAGGTCGAGATATTGAGACCATCCTGGCCAAGATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGGCATACGCCTGTAGTCCCAGCTACTTGCGAGGCTGAGGCAGGAGGATCGCTTGAACCCAGGAGGTGGAGGCTGCCGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGACGACAGAGCAAGACTCCACCTCAAAAAACAACAACAACAACTAGACCACCTACCACAAATCACTGCAGTATGCTACCAACACAATGTGTGCAAGTGGCATATTATAGAGTAACTACTGTTATTCAGATAACCACCTCACAATGTTTCTTTTATCTGAACCTATCCATTTCATCAGTACCCACTCATAACCGTTTGTTGCAGTCTGAATCAACAAGGGATGTGGAACCCAAACTTCAGCCATAGCCAATGTTCTGTGGACACTGAGTTCTGTAGGTCTTCATGGCAGGTGTGCACCCTTCTGGACAGGACCTTCCCTGACAGCTTCCAGCATAACCCTGGCTGTTGGCAAGATGTCCTCTTATAGTCAACAGGCCCTTGGGCAAGGATGTCTCAGCACCTATGTGTAGATAATACATAGGGAGCTCCCTTAATGTGCCCGGACCCATACCAGGCAGAGTGGGAAACAAGAAGTGAGGAAGAACAGCCCCCAAGGACAGGTCTGAGAGGCTCATGCTGCATACCTCTGGACACCCACCTGTGCCTGTGCCCATAGACACAAAACAGTGGGGAGCAGGGCCATGGTGGGAGTGGGAATCTCAGGACTCCTAGCTTCCCATAATATCCATTCAGGGACAAAAGCATGGCTTTCATAGTCCACGGCTATGCCCTAGAGATCTAGGAGTCCTTTCTTCCCTGTCTGTCCCATGGAGAATGACCATCAGCCTACAGACCTGGTCCAGCAATAGTAATATAGATACTATACAGCCTCAAGGGCAACCACTATCAAGCCAACACCCCAAGGCCACTCTCAGCCTCCACCCTCTTTTGGTAAGGGGCTGGAATTACTGCAGAGTAGCCAACTTGGTGACCCTCTGGGTCACCTCAGCCCAGGGGCCCAGAGTGGCTCTCTGTGGTTAACCAGTCTAACAGATAGGGCATCTGCAGCAGAGGCAGGCAGCTGTGATGACATGGAAAGGACACGGCACTGGGAACTGAGTTCCAGACACAGCTTTGTCACTGACTCGTGTGTGTTCATGAGCAAGGCACGCAAGTCAGGACTCAGGTCGCCATCTGTGAAATGAGGATAACCATCCTTGCCTCATATGAAGGGCAGCTGTGAAAATGCAGAGAATGGAAGGACTACAATATAAGCCTCAAGACACTCTGTTCTGAAGCTTTCCTTTGGTCGCAGGAAAAGGAAAATCTCACATTCAGCCCCAATCAGGATCAGGTGGCAGAGGTGACAGTGATATTGCAGGCAGCCTCAAGACTTCCCTCTGTGCTGGAGATGGCCTCATGTTGCAGCTGAGACATCACCAGAGGCCCCTCTCCTAAAGCTCAGCCCCACCCCCCAGCTAATCTGCTTCCTCTGTCAGGGCCAGCTTGGCTCAAGCTACCCCAGGAGGCCTGGGAACCCTACAACTTCAGCCCAACAGCTGGGGTGGGGTATGTTCTATTCCCACTAGCATCAACCACACCATGGTGGCCTGTCATGGAACACCTAGCTCGCCCTTTCTCTCAACGGCCTAGGACCCAGGTGGGTCAGGATTATTACAGGGTGTGTGCACTGAAGCTACGCAAAGTGAAGACTGGGGAGGGGTACCTGGGGCACTAGATATTAACTGGCTCTCCTACTCTCCAAACAGCTCAGTAACAAGTCCCTTGACAGAGACACAGCAGGCTGGACCCCCTACAGCTATGTGAACGTGTTAGGTCAGTAGTGGTGTGAGTCTGGTCCCCACCATCATGTCCCACCCTATTCTTCTTCCATATTGAGAAGCACCCAGCTTGAAGGGACAGGGTTATGAGTTCTGAACATGGTTTCCCCCAGGGAGAAATTTTGGCTCTCACAAGCAGATGAAGCCCAAGAATCCCTTTCCATTACTATATTAGGGCTAAGTCCCTGCTATGACCCAGGGACCATAAGGGAGAAAACCAGGGCCAGGGTGTAGGGATTCCAGATGGAAGCAAAAGACACACTCACCATCTGGATAGGAACCTCTGCTTGACCCAGGCCCTACCAAGGTGCTCCTTTCAAGGGCTTCTTCCCCCTGCCTCCTCCCTGGTGGAGGAGCACTAATTCCTGCAGAGGGAGGGAGGGAGGGAAGGAGAGGGGAAACAAGGCAGATGACCTTGGCTCTAACAGAGCCCCTGGCCCCGCTGGCCCTGGCCCCTCTGGATGCTATACACAGAGGCCCCCAAGTCCTCCCAGCCTGCCTCACCCTGACCCTGGCCCACTTGTGTACTTCCTACCCCCTTCCCCTGCTATACCAGGGCCCTGGGAATAATGGCTCCTCCCTGTCATTCCTCTCACTAGACTCCCATTTCCAGATCAGTGCCCTGGAGGCCAGGTACCCGCCCGAGGACTTCTACATTGAACTTAGACACCTCAGCCGCCCCGCTGAGCCACACTCACCAGGTCAGACCCCAGCCCTACCCTCCACCCCCTCATGCCAGACCAGACCCAGCACCTGCCCTAATCCCCATCCCTGCACCTTGACCCCCACCCTGTGGTCCCAGAACTCTCCCTTTTAAGCCCTCTTCCCTCCCAACATGTCTACCAGCTCAATCCCCTATCTAAAGATGGAAACCTGTCTGGATCTTCCCCATCACCCATTCTGTTCCCATAGTGAACGGTGGATGTGAACAAACAGGCTATTTAGGGTGGAGAAGATACAACAAAACTGCCCTCCCTACAGGCCACAAAATACAATCCTACACCTTTCAAAAATGACTTGGGGATGGCGACATCTTTGGGGTTCTCTGGGCCCTGTTGGAGTGGATAACAGGGAGTTAGCTCTCTGGCCAATAAAGTCCAATGTCTCCCAGAGACTCCAGAAACCCCAGTGGCCCAAGCCAAGCTTTCTCAAATCACAGGGTAGGGTTGTCAAACAGGGATCTGGAGAGGCTGGGGCAGGATGTATCAACCAACATCACCTGTACTCATGTACTGAGTACAGCCTGGGCTGAAATCTGGTGGCTTGGGAGACACACACACAAGAGACTTGGAAAGTTAGCCCTGATTATGGGAACATGTGGGTAGGAGTTACAGAAGGTATCATGGGAACAAGTGCAATGAATGAACAGAGAATGTGGCCTCCCTACAATGTGGCTCCTCTGGGGCACCCTGGGGCAGGGCCTTGGTATACCAGACAACTCTAGGCCTGACCTCAGGCTCTAGGTGGCTTCTAGAACTCTAAGGAAACTGAGCTGCTCTACCAATCCCTGCAGGTCCCTGGGTCCAGTAATACCAGGAAGGGTGAATGTTCTGAATTCATCTGCCCACTGAGCAGGCATGGGCTGCATGGACCCTGGGCCTATACTCAGGAGGCTGTGTTATTAGCTGTGGGTCCCCTGGACAGTATCTAGGGCATTTAATAACCCCACCAACTACAATCTCTCCCATTCCAGCATATACACACACACACAGCCCCACCACCACCACCCTGTATCTCTTTCTACAAGGGAGTATCCTCTGAACTAGGCCAGATTTCTCCCTGCTTTACAGATCTCACTCTTCAACTAGCGTAGCCAGAGCGCCATGCGCTGGCATTTGTCTTACACCCAGGCAGGCTGGTATCCAGTGAGAGAGAATACTTGGAGAGATCTGGGCTCTAACTGTAACTCAGCTTCTCACTTGCTAGTGTGGTTTTGGACAAGCCACTGTTGCTCTTTGGGCCTGTTCCCTGTTCTGTAAAAAGGAAAAGTTAATACCCTAGCCAGCTTCCCTCAGGAAGGGCAAAGGAAGCCCTTGTCTGGCATAAAGTGCTGAACTAATGCCAGCATATAGGCAGTTGCAGGCATGATTCTGAAGGACACAGGTACCTATAAGCCTCTCAGAAAAAACAGCAAATTTGAGGCTGGGTACGGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACGTGACGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCCATCTGTTAAAAATACAAAAAAATTAGCTGGGAGTGGTGGTGCATGCCTGTAGTCCCAGCTACTCAGGAGGTTGAGACAGGAGAATCGATTGAACCTGGAAGGTGGAGGTTGTAGTGAACAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACACAGCGAGACTCCATCTCAAAAAAAAAGAAAAAAAGAAAAATAGCAAACTTAAAAGAAAAACTTGGGCCTGGTTCTGCCATATCTCTCAGTAATATGTGGAACGTAGGCAGATAGGAGTAGACGCTTTCAAATTCAACATGGGAACTCTACGTAGAGGAGCGATAGCAACAGGGTGGTCTTCAGTGTCAGAAACTGGGAAGAGTCAAGGAGAGTCAAACTGTATTTTAGTAAGTACTTGCTGCAGGCCTTGCTTGGTGCTGTGTCCTCAGTTAAAAGCTAGAAGAAAAAATTGCTCTGACTTTGAGCCAGAGTCATTACTGTCCCAACCTAGAAATGCCAAACAATTTCTTTTCTGGGATCACCAGCAGCAAAGAACCCAAGCTTAGTCCCTGAAGCCTCTGGCTGAGGCTCAGGGCCATCATGCATTGTTGGAGCCTAGGAAAAAACTGACAGCCGAAAGGTAGAAAGAAATCCTTGGGGCTGAAAACACTGGTAATACTTTTCAAAAACAATTCTACATTATGTGCAAATGGCACACCCCAAAAAATGAGTAACTAAGAGAACTGGCTATGGGAGGGAATGTCTGTACATCCTACAAAGATGACTAATCAAGAACCTCAGCCACCTGTCTCCCTCTGTTTCTCTCTGGCTACCCTCAGATAAGCCTTGGATCCAGGAGAGGACAGACAGGACCAGAGCTGAGAGGTGATAAATACTGTCTTCAAACCCATGCCAAATTCCAACAGAACTGTGATTTGTAATGTCATACAACTTTCCCTCAAGCCAAGAACTGGTTCTGCTTCATTCCTTATCCTATACCCTTGGAGCCTGGAGTTTCACCTGCAGGGAATGGCATCAGAACAGCCTTTTATTCCTTCCTGAAAGACACTCCCCTAGGGTGAAGGTTAAAGGGAAGGAGTGCTGAATATGCCGGGGGTCGCTGTAGCTTATGAGCCTTTTAATAATTCCTATAATCAAAACAATTTCAGATGGATTAAACCCAGAATCATTTATCAAAACAATTTCAGGTAGATTAAACCCCCAGAATCATTTTCTAGCAATAAACAACTATTTATTTTCTGGGTAGGGGAGAAGGGGGGGGAAAAGCAAGAAAAGAAAGAAGAACACAAGCAGTCTAAGTAAACCTCACCCCCATATTTTCTTTCCTTACATGTTATTTTTACACAG
Seq C2 exon
GTGCTTGTGGAATGGATAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.142
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(18.9=8.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development