MmuEX0028586 @ mm10
Exon Skipping
Gene
ENSMUSG00000036466 | Megf11
Description
multiple EGF-like-domains 11 [Source:MGI Symbol;Acc:MGI:1920951]
Coordinates
chr9:64693761-64700153:+
Coord C1 exon
chr9:64693761-64693997
Coord A exon
chr9:64695364-64695482
Coord C2 exon
chr9:64700097-64700153
Length
119 bp
Sequences
Splice sites
3' ss Seq
GCTCCTTGTTCTCTTCCCAGATT
3' ss Score
9.48
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
CTGCCCTCATGATGGATGAGCTGAATCCCTACACCAAGATCAGTCCAGCTCTGGGAGCAGAGCGGCACTCAGTGGGTGCTGTCACCGGCATCGTTCTCCTGTTGTTCCTGGTGGTGGTGCTGCTGGGCCTGTTTGCCTGGCGACGGAGGCGGCAGAAAGAGAAAGGCCGTGACCTGGCTCCCCGAGTCTCCTACACCCCAGCCATGAGGATGACCAGCACAGACTACTCTCTCTCAG
Seq A exon
ATTTGTCTCAAAGTAGCAGCCATGCCCAGTGCTTTTCCAATGCCAGCTACCACACACTGGCGTGTGGGGGGCCTGCCACCAGCCAGGCCAGCACTCTGGACAGGAACAGCCCCACCAAG
Seq C2 exon
GCACTTGTGGAATGGACAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036466_MULTIEX2-2/4=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=0.325 C2=0.280
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(14.3=6.2)
A:
NO
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATGAGCTGAATCCCTACACC
R:
CTGACGTCTGTCCATTCCACA
Band lengths:
250-369
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types