HsaEX0041014 @ hg19
Exon Skipping
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:7593]
Coordinates
chr5:16783444-16818276:-
Coord C1 exon
chr5:16818118-16818276
Coord A exon
chr5:16794755-16794942
Coord C2 exon
chr5:16783444-16783578
Length
188 bp
Sequences
Splice sites
3' ss Seq
GTCTCACTCTGTGCTTGCAGACC
3' ss Score
9.58
5' ss Seq
CAGGTAACG
5' ss Score
10.52
Exon sequences
Seq C1 exon
GTATTCACTTACAAGCAGAGCACAATTACCCACCAGAAGGTGACTGCTATGCACCCCACGAACGAGGAGGGCGTGGATGACATGGCGTCCTTGACAGAGCTCCATGGCGGCTCCATCATGTATAACTTATTCCAGCGGTATAAGAGAAATCAAATATAT
Seq A exon
ACCTACATCGGCTCCATCCTGGCCTCCGTGAACCCCTACCAGCCCATCGCCGGGCTGTACGAGCCTGCCACCATGGAGCAGTACAGCCGGCGCCACCTGGGCGAGCTGCCCCCGCACATCTTCGCCATCGCCAACGAGTGCTACCGCTGCCTGTGGAAGCGCCACGACAACCAGTGCATCCTCATCAG
Seq C2 exon
TGGTGAAAGTGGGGCAGGTAAAACCGAAAGCACTAAATTGATCCTCAAGTTTCTGTCAGTCATCAGTCAACAGTCTTTGGAATTGTCCTTAAAGGAGAAGACATCCTGTGTTGAACGAGCTATTCTTGAAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555-'6-8,'6-7,8-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.240 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(15.3=52.8)
A:
PF0006316=Myosin_head=FE(33.9=100)
C2:
PF0006316=Myosin_head=FE(24.6=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGGTGACTGCTATGCACCC
R:
AGCTCGTTCAACACAGGATGT
Band lengths:
245-433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)