HsaEX0042204 @ hg19
Exon Skipping
Gene
ENSG00000072864 | NDE1
Description
nudE nuclear distribution E homolog 1 (A. nidulans) [Source:HGNC Symbol;Acc:17619]
Coordinates
chr16:15788022-15793679:+
Coord C1 exon
chr16:15788022-15788113
Coord A exon
chr16:15790566-15790717
Coord C2 exon
chr16:15793586-15793679
Length
152 bp
Sequences
Splice sites
3' ss Seq
AAAAGTGTATTTCTGTCCAGGCA
3' ss Score
4.78
5' ss Seq
GGGGTCAGT
5' ss Score
3.99
Exon sequences
Seq C1 exon
GCCTGGACGACTCCACCGGGGGGACCCCCCTCACACCTGCGGCCCGGATATCAGCCCTCAACATTGTGGGAGACCTACTGCGGAAAGTCGGG
Seq A exon
GCACTGGAGTCCAAACTCGCTTCCTGCCGGAACCTCGTGTACGATCAGTCCCCAAACCGAACAGGTGGCCCAGCCTCTGGGCGGAGCAGCAAGAACAGAGATGGCGGGGAGAGACGGCCAAGCAGCACCAGCGTGCCTTTGGGTGATAAGGG
Seq C2 exon
GTTGGGGAAGCGCCTGGAATTTGGGAAGCCGCCTTCACACATGTCTTCATCGCCGCTGCCGTCAGCCCAGGGGGTAGTCAAGATGTTGCTTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000072864-'11-15,'11-14,14-15
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.555 A=0.794 C2=0.871
Domain overlap (PFAM):
C1:
PF077956=DUF1635=PD(18.4=83.9),PF048808=NUDE_C=FE(19.2=100)
A:
PF048808=NUDE_C=FE(25.0=100)
C2:
PF048808=NUDE_C=PD(10.3=65.6)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTGGACGACTCCACCG
R:
CTAAAGCAACATCTTGACTACCCCC
Band lengths:
186-338
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)