HsaEX0042216 @ hg19

Exon Skipping

Gene

ENSG00000166579 | NDEL1

Description

nudE nuclear distribution E homolog (A. nidulans)-like 1 [Source:HGNC Symbol;Acc:17620]

Coordinates

chr17:8347578-8350220:+

Coord C1 exon

chr17:8347578-8347675

Coord A exon

chr17:8349029-8349182

Coord C2 exon

chr17:8350072-8350220

Length

154 bp

Sequences

Splice sites

3' ss Seq

CCCACTTTGTTTCTGATTAGCTT

3' ss Score

6.54

5' ss Seq

AAGGTAATT

5' ss Score

8.83

Exon sequences

Seq C1 exon

GCTTTCTTGATCATGGATGGTGAAGATATACCAGATTTTTCAAGTTTAAAGGAGGAAACTGCTTATTGGAAGGAACTTTCCTTGAAGTATAAGCAAAG

Seq A exon

CTTCCAGGAAGCTCGGGATGAGCTAGTTGAATTCCAGGAAGGAAGCAGAGAATTAGAAGCAGAGTTGGAGGCACAATTAGTACAGGCTGAACAAAGAAATAGAGACTTGCAGGCTGATAACCAAAGACTGAAATATGAAGTGGAGGCATTAAAG

Seq C2 exon

GAGAAGCTAGAGCATCAATATGCACAGAGCTATAAGCAGGTCTCAGTGTTAGAAGATGATTTAAGTCAGACTCGGGCCATTAAGGAGCAGTTGCATAAGTATGTGAGAGAGCTGGAGCAGGCCAACGACGACCTGGAGCGAGCCAAAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000166579_MULTIEX1-2/2=C1-C2

Average complexity

S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.132 A=0.108 C2=0.020

Domain overlap (PFAM):

C1:

PF079267=TPR_MLP1_2=PU(34.2=93.1),PF152721=BBP1_C=PU(12.1=58.6),PF102414=KxDL=PU(10.0=24.1),PF104734=CENP-F_leu_zip=PU(7.2=34.5)

A:

PF079267=TPR_MLP1_2=FE(64.6=100),PF152721=BBP1_C=FE(37.2=100),PF104734=CENP-F_leu_zip=FE(39.8=100),PF102414=KxDL=FE(72.9=100),PF138701=DUF4201=PU(34.4=59.6),PF0218313=HALZ=PU(75.0=40.4)

C2:

PF152721=BBP1_C=FE(35.8=100),PF104734=CENP-F_leu_zip=FE(38.3=100),PF102414=KxDL=PD(14.3=20.0),PF138701=DUF4201=FE(54.4=100),PF0218313=HALZ=PD(17.9=10.0)

Main Inclusion Isoform:

ENSP00000299734