HsaEX0044836 @ hg38
Exon Skipping
Gene
ENSG00000115947 | ORC4
Description
origin recognition complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:8490]
Coordinates
chr2:147943436-147972829:-
Coord C1 exon
chr2:147972739-147972829
Coord A exon
chr2:147958791-147958866
Coord C2 exon
chr2:147943436-147943522
Length
76 bp
Sequences
Splice sites
3' ss Seq
CATAAACTTTTCATATTTAGTTA
3' ss Score
5.96
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
Exon sequences
Seq C1 exon
ACACTTAAGTGAGCTGCTGAAAAGAACTGCTCTCCATGGAGAGAGTAACTCTGTCCTTATTATCGGACCCCGAGGATCAGGAAAAACTATG
Seq A exon
TTAATAAATCATGCTTTGAAAGAACTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATG
Seq C2 exon
TATCTCTCAGAAGATAGAAGTGTGCAAGAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115947_MULTIEX1-2/7=C1-7
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF131911=AAA_16=FE(19.4=100)
A:
PF131911=AAA_16=FE(16.1=100)
C2:
PF146291=ORC4_C=FE(14.6=100)
Main Skipping Isoform:
ENST00000535373fB4885
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAGCTGCTGAAAAGAACTGC
R:
TAGCATGTGTAATGACCGCAGG
Band lengths:
167-243
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development