HsaEX0046264 @ hg38
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:654080-657023:+
Coord C1 exon
chr4:654080-654154
Coord A exon
chr4:655940-656006
Coord C2 exon
chr4:656874-657023
Length
67 bp
Sequences
Splice sites
3' ss Seq
CCCCTGCTCTCTGCCCACAGCAC
3' ss Score
11.83
5' ss Seq
TTTGTGAGT
5' ss Score
5.91
Exon sequences
Seq C1 exon
GAATTTTTTGACGTGTGGTCTGTGCTGATGGGAGAGTCCCAGCCGTACTCGGGCCCACGCACGCCTGATGGCCGG
Seq A exon
CACACCCTCAGCCGATCACTGGGCCCTGGCCAGCGGCCTTCCAAGCTACGTGGCAGAAAGCGGCTTT
Seq C2 exon
GAAGGGGCCCTGGACGACTCCGGGTGGCTCATCAAGAATGTGCTGTCCATGCCCATCGTCAACAAGAAGGAGGAGATTGTGGGAGTCGCCACATTTTACAACAGGAAAGACGGGAAGCCCTTTGACGAACAGGACGAGGTTCTCATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256_MULTIEX1-2/3=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=0.000 C2=0.019
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(13.5=100)
A:
PF0159021=GAF=FE(12.4=100)
C2:
PF0159021=GAF=FE(27.5=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGTGCTGATGGGAGAGTCC
R:
GCTTCCCGTCTTTCCTGTTGT
Band lengths:
175-242
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development