HsaEX0046265 @ hg38
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:654080-657023:+
Coord C1 exon
chr4:654080-654154
Coord A exon
chr4:656245-656292
Coord C2 exon
chr4:656874-657023
Length
48 bp
Sequences
Splice sites
3' ss Seq
TTTTTCTGATGCTTTTTCAGATT
3' ss Score
11.06
5' ss Seq
CAGGTATCT
5' ss Score
7.33
Exon sequences
Seq C1 exon
GAATTTTTTGACGTGTGGTCTGTGCTGATGGGAGAGTCCCAGCCGTACTCGGGCCCACGCACGCCTGATGGCCGG
Seq A exon
ATTTGTAACATCATGAATGCTTCCGCTGACGAAATGTTCAAATTTCAG
Seq C2 exon
GAAGGGGCCCTGGACGACTCCGGGTGGCTCATCAAGAATGTGCTGTCCATGCCCATCGTCAACAAGAAGGAGGAGATTGTGGGAGTCGCCACATTTTACAACAGGAAAGACGGGAAGCCCTTTGACGAACAGGACGAGGTTCTCATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256_MULTIEX1-3/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=0.000 C2=0.019
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(13.5=100)
A:
PF0159021=GAF=FE(10.3=100)
C2:
PF0159021=GAF=FE(27.5=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGTGCTGATGGGAGAGTCC
R:
CGACTCCCACAATCTCCTCCT
Band lengths:
145-193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development