HsaEX0057550 @ hg19
Exon Skipping
Gene
ENSG00000107290 | SETX
Description
senataxin [Source:HGNC Symbol;Acc:445]
Coordinates
chr9:135218077-135224822:-
Coord C1 exon
chr9:135224639-135224822
Coord A exon
chr9:135221648-135221858
Coord C2 exon
chr9:135218077-135218186
Length
211 bp
Sequences
Splice sites
3' ss Seq
CCCATTTTATTTTCCTCTAGGTT
3' ss Score
11.73
5' ss Seq
TTAGTGAGT
5' ss Score
5.79
Exon sequences
Seq C1 exon
GTACAGAATGAGCACATGTTGTTGGTGTACGCCAGGTGGTGCTTCCACCATTGACTTCCTAAAGCGCTATGCTTCCAACACTCCGTCCGGTGAATTTCAAACAGCCGACGAAGACCTCTGCTACTGCTTGGAGTGTGTGGCTGAGTACCACAAAGCAAGAGATGAATTGCCATTCTTGCATGAG
Seq A exon
GTTTTATGGGAATTAGAAACCTTACGTCTCATAAATCACTTTGAAAAATCCATGAAGGCAGAAATTGGAGATGATGATGAGTTATATATAGTAGACAATAATGGAGAGATGCCACTGTTTGACATCACTGGGCAAGACTTTGAAAATAAGCTTCGAGTTCCTCTTCTTGAAATACTGAAATATCCTTACTTGCTTCTACATGAACGTGTTA
Seq C2 exon
ACGAGTTATGTGTTGAAGCACTTTGTCGGATGGAACAAGCCAATTGCTCCTTTCAGGTGTTTGATAAACATCCAGGGATCTATTTGTTTTTAGTCCATCCCAATGAAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107290_CASSETTE4
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127262=SEN1_N=PU(11.1=49.2)
A:
PF127262=SEN1_N=FE(26.8=100)
C2:
PF127262=SEN1_N=FE(13.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGAATGAGCACATGTTGTTGG
R:
CATTTCATTGGGATGGACTAAAAACA
Band lengths:
292-503
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)