HsaEX0057925 @ hg19
Exon Skipping
Gene
ENSG00000095370 | SH2D3C
Description
SH2 domain containing 3C [Source:HGNC Symbol;Acc:16884]
Coordinates
chr9:130513451-130536746:-
Coord C1 exon
chr9:130536269-130536746
Coord A exon
chr9:130523890-130523929
Coord C2 exon
chr9:130513451-130513579
Length
40 bp
Sequences
Splice sites
3' ss Seq
CTTGTCTTTTCTCCTTCCAGGGC
3' ss Score
12.92
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
AGTTCTTCAAGTTCAAGGGCTTTGGGAGTCTCTCCAACCTCCCTCGGTCCTTCACTCTGAGACGATCCTCAGCTTCCATCAGTAGGCAGTCCCATTTGGAGCCTGACACCTTTGAAGCCACGCAGGATGACATGGTGACGGTGCCCAAGAGTCCCCCAGCCTATGCCCGCTCCAGTGACATGTACAGCCACATGGGCACCATGCCTCGCCCCAGCATCAAGAAAGCACAGAACTCACAGGCTGCCCGGCAGGCCCAGGAGGCGGGTCCCAAGCCCAACTTGGTACCCGGAGGTGTACCCGACCCCCCAGGCTTGGAGGCAGCCAAAGAGGTGATGGTGAAGGCCACTGGCCCTCTAGAGGACACCCCAGCAATGGAACCCAACCCTTCAGCAGTGGAGGTAGACCCCATCAGAAAGCCTGAGGTCCCCACAGGAGACGTAGAAGAGGAGAGACCTCCCAGGGACGTGCACTCAGAAAG
Seq A exon
GGCTGCTGGAGAGCCAGAGGCTGGCAGCGACTATGTGAAG
Seq C2 exon
TTCTCCAAGGAGAAGTACATCCTGGACTCATCGCCAGAGAAACTCCACAAGGAATTGGAGGAGGAGCTCAAACTCAGCAGCACGGATCTCCGCAGCCATGCCTGGTACCATGGCCGCATCCCCCGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095370-'5-15,'5-11,11-15
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.894 A=0.268 C2=0.033
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0001719=SH2=PU(9.9=18.6)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCAGCAGTGGAGGTAGACCC
R:
CCTTGTGGAGTTTCTCTGGCG
Band lengths:
145-185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)