HsaEX0062217 @ hg19
Exon Skipping
Gene
ENSG00000136738 | STAM
Description
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:HGNC Symbol;Acc:11357]
Coordinates
chr10:17702463-17730172:+
Coord C1 exon
chr10:17702463-17702547
Coord A exon
chr10:17726674-17726749
Coord C2 exon
chr10:17730026-17730172
Length
76 bp
Sequences
Splice sites
3' ss Seq
TACTTTTCTCATTTTTTTAGACC
3' ss Score
9.24
5' ss Seq
ACTGTGAGT
5' ss Score
7.94
Exon sequences
Seq C1 exon
AGAAAGCAACCAGCGAGATGAATACTGCTGAGGACTGGGGCCTCATTTTGGATATCTGTGATAAAGTTGGTCAGTCTCGCACTGG
Seq A exon
ACCTAAGGATTGTCTTCGGTCTATTATGAGAAGAGTGAACCACAAAGATCCTCACGTTGCTATGCAGGCTTTGACT
Seq C2 exon
GGTCATCCTAAAGTATGTGAAAAATTAAAGGCTCTTATGGTTGAATGGACAGATGAATTTAAGAATGATCCACAGCTTAGTCTAATATCAGCAATGATTAAGAACCTTAAGGAACAAGGAGTTACGTTCCCAGCTATTGGCTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136738_MULTIEX1-4/7=1-6
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.184 A=0.116 C2=0.027
Domain overlap (PFAM):
C1:
PF0079014=VHS=FE(20.7=100)
A:
PF0079014=VHS=FE(18.5=100)
C2:
PF0079014=VHS=PD(28.9=79.6)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGGCCTCATTTTGGATATCTGT
R:
GCTGGGAACGTAACTCCTTGT
Band lengths:
183-259
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)