HsaEX0063577 @ hg38
Exon Skipping
Gene
ENSG00000136560 | TANK
Description
TRAF family member associated NFKB activator [Source:HGNC Symbol;Acc:HGNC:11562]
Coordinates
chr2:161179614-161223991:+
Coord C1 exon
chr2:161179614-161179761
Coord A exon
chr2:161204675-161204793
Coord C2 exon
chr2:161223915-161223991
Length
119 bp
Sequences
Splice sites
3' ss Seq
AAGAGGTTTTTGTCTTGCAGATA
3' ss Score
7.86
5' ss Seq
AAGGTAGAC
5' ss Score
7.07
Exon sequences
Seq C1 exon
ACCTGTCATTTACTCCATCCTTTATAGTGATGCTACAGGACGAAGAGGAATGGATAAAAACATTGGCGAGCAACTCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAGATTCTGCAGTAAAAGAATTACAGCAAAAG
Seq A exon
ATAACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATTTGACTCTTGATCAGCCACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAAAG
Seq C2 exon
GTAAGAAGACAAGAGGTTTCTTCTCCTAGAAAAGAAACTTCAGCAAGGAGTCTTGGCAGTCCTTTGCTCCATGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136560_MULTIEX2-5/11=C1-7
Average complexity
C3
Mappability confidence:
91%=100=91%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.282 A=0.525 C2=0.899
Domain overlap (PFAM):
C1:
PF040127=PspA_IM30=PU(46.3=93.9),PF125063=DUF3713=PU(39.5=90.9),PF041569=IncA=PU(39.2=87.9)
A:
PF125063=DUF3713=PD(29.5=70.0),PF041569=IncA=PD(33.7=82.5)
C2:
PF041569=IncA=PD(10.9=57.7),PF128452=TBD=PU(9.8=19.2)
Main Skipping Isoform:
ENST00000405852fB6915
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTGTCATTTACTCCATCCTTT
R:
ATGGAGCAAAGGACTGCCAAG
Band lengths:
220-339
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development