HsaEX0070245 @ hg38
Exon Skipping
Gene
ENSG00000141968 | VAV1
Description
vav guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:12657]
Coordinates
chr19:6822221-6825121:+
Coord C1 exon
chr19:6822221-6822329
Coord A exon
chr19:6822419-6822514
Coord C2 exon
chr19:6825053-6825121
Length
96 bp
Sequences
Splice sites
3' ss Seq
GCCTCTCCCCTCGCTCTCAGCCC
3' ss Score
8.87
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
CGACACGGTGGAGGAGGATGAGGACCTGTATGACTGCGTGGAGAATGAGGAGGCGGAAGGCGACGAGATCTATGAGGACCTCATGCGCTCGGAGCCCGTGTCCATGCCG
Seq A exon
CCCAAGATGACAGAGTATGACAAGCGCTGCTGCTGCCTGCGGGAGATCCAGCAGACGGAGGAGAAGTACACTGACACGCTGGGCTCCATCCAGCAG
Seq C2 exon
CATTTCTTGAAGCCCCTGCAACGGTTCCTGAAACCTCAAGACATTGAGATCATCTTTATCAACATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141968_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.286 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=PU(8.3=37.8)
A:
PF0062115=RhoGEF=PU(11.4=62.5)
C2:
PF0062115=RhoGEF=FE(12.6=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GACACGGTGGAGGAGGATGAG
R:
TCAATGTCTTGAGGTTTCAGGA
Band lengths:
155-251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development