Special

MmuEX6078788 @ mm10

Exon Skipping

Gene
Description
vav 1 oncogene [Source:MGI Symbol;Acc:MGI:98923]
Coordinates
chr17:57297049-57298840:+
Coord C1 exon
chr17:57297049-57297157
Coord A exon
chr17:57297246-57297341
Coord C2 exon
chr17:57298772-57298840
Length
96 bp
Sequences
Splice sites
3' ss Seq
TCTATGGTCTCTGCTCACAGCCC
3' ss Score
7.94
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
Exon sequences
Seq C1 exon
TGACACCGCAGAGGAAGACGAGGACCTTTATGACTGCGTGGAAAATGAGGAGGCAGAGGGGGACGAGATCTACGAGGACCTAATGCGCTTGGAGTCGGTGCCTACGCCA
Seq A exon
CCCAAGATGACAGAGTATGATAAGCGCTGCTGCTGCCTGCGGGAGATCCAGCAGACGGAGGAGAAGTATACAGACACACTGGGCTCCATCCAGCAG
Seq C2 exon
CACTTCATGAAGCCTCTGCAGCGATTCCTTAAGCCTCAAGACATGGAGACCATCTTTGTCAACATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000034116-'10-14,'10-11,11-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.324 A=0.031 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
PF0062115=RhoGEF=PU(11.4=62.5)
C2:
PF0062115=RhoGEF=FE(12.6=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGAGGAAGACGAGGACCTT
R:
ATGTTGACAAAGATGGTCTCCATGT
Band lengths:
167-263
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types