HsaEX0070348 @ hg19
Exon Skipping
Gene
ENSG00000136059 | VILL
Description
villin-like [Source:HGNC Symbol;Acc:30906]
Coordinates
chr3:38038974-38040541:+
Coord C1 exon
chr3:38038974-38039176
Coord A exon
chr3:38039581-38039659
Coord C2 exon
chr3:38040403-38040541
Length
79 bp
Sequences
Splice sites
3' ss Seq
CTGGGTTCCTGTCCCCCCAGTGT
3' ss Score
8.38
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
Exon sequences
Seq C1 exon
GGGCTGGCTTTGACCTACAGCCTCCGGGACAGGGAACGTGGTGGTGGTCGTGCACAGATTGGTGTGGTGGATGATGAGGCCAAAGCCCCGGACCTCATGCAGATCATGGAGGCTGTGCTGGGCCGCAGGGTGGGCAGCCTGCGTGCCGCCACGCCCAGCAAGGATATCAACCAGCTGCAGAAGGCCAATGTTCGCCTGTACCA
Seq A exon
TGTCTATGAGAAGGGCAAAGACCTGGTGGTCCTGGAGTTGGCGACCCCCCCACTGACCCAGGACCTGCTGCAGGAGGAG
Seq C2 exon
GGCTTCATCCAGGCCAAGGGCTACCCGACCTACACCAACGTGGAGGTGGTGAACGACGGCGCCGAGTCGGCCGCGTTCAAGCAGCTCTTCCGGACTTGGTCTGAGAAGCGGCGCAGGAACCAGAAGCTCGGCGGGAGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136059_MULTIEX1-1/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=0.000 C2=0.087
Domain overlap (PFAM):
C1:
PF0062617=Gelsolin=PD(41.6=47.1)
A:
PF0062617=Gelsolin=PU(19.7=55.6)
C2:
PF0062617=Gelsolin=PD(34.2=55.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGTGGATGATGAGGCCAAA
R:
ACGTTGGTGTAGGTCGGGTAG
Band lengths:
181-260
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)