HsaEX1025337 @ hg38
Exon Skipping
Gene
ENSG00000072864 | NDE1
Description
nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619]
Coordinates
chr16:15664736-15677949:+
Coord C1 exon
chr16:15664736-15664861
Coord A exon
chr16:15667286-15667439
Coord C2 exon
chr16:15677801-15677949
Length
154 bp
Sequences
Splice sites
3' ss Seq
GATTAACAATTTTGCTGTAGGGC
3' ss Score
5.79
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
ACACCATGCCACAAGGAGAGTGATCTCTTCCCCTGTTTTCACAATGGAGGACTCCGGAAAGACTTTCAGCTCCGAGGAGGAAGAAGCTAACTATTGGAAAGATCTGGCGATGACCTACAAACAGAG
Seq A exon
GGCAGAAAATACGCAAGAGGAACTCCGAGAATTCCAGGAGGGAAGCCGAGAATATGAAGCTGAATTGGAGACGCAGCTGCAACAAATTGAAACCAGGAACAGAGACCTCCTGTCCGAAAATAACCGCCTTCGCATGGAGCTGGAAACCATCAAG
Seq C2 exon
GAGAAGTTTGAAGTGCAGCACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGACCAAAGCCATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACGACCTGGAAAGAGCCAAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000072864-'11-40,'11-34,12-40
Average complexity
S
Mappability confidence:
92%=75=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.686 A=0.738 C2=0.260
Domain overlap (PFAM):
C1:
PF079267=TPR_MLP1_2=PU(32.5=89.3),PF104734=CENP-F_leu_zip=PU(24.2=78.6),PF040127=PspA_IM30=PU(11.9=35.7),PF088265=DMPK_coil=PU(3.6=7.1)
A:
PF079267=TPR_MLP1_2=FE(66.2=100),PF104734=CENP-F_leu_zip=FE(56.0=100),PF040127=PspA_IM30=FE(60.7=100),PF088265=DMPK_coil=FE(91.1=100)
C2:
PF040127=PspA_IM30=PD(18.4=29.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CACCATGCCACAAGGAGAGTG
R:
GCTTGCTCCAGCTCTCTGATG
Band lengths:
247-401
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains