MmuEX0031222 @ mm10

Exon Skipping

Gene

ENSMUSG00000022678 | Nde1

Description

nudE neurodevelopment protein 1 [Source:MGI Symbol;Acc:MGI:1914453]

Coordinates

chr16:14169452-14183612:+

Coord C1 exon

chr16:14169452-14169575

Coord A exon

chr16:14170338-14170491

Coord C2 exon

chr16:14183476-14183612

Length

154 bp

Sequences

Splice sites

3' ss Seq

TATTTGCAATACTGCTGCAGGGC

3' ss Score

4.14

5' ss Seq

AAGGTGAGG

5' ss Score

9.16

Exon sequences

Seq C1 exon

ACATCATGCCACAGGAAGAGTGAGCTTTTGCCCATTTTACCATGGAGGACTCGGGAAAGACCTTTGAATCAGAGGAGGAAGAAACAAACTATTGGAGAGACCTGGCCATGACCTACAAACAGAG

Seq A exon

GGCAGAGAATACTCAGGAAGAACTCAGAGAGTTCCAGGAAGGAAGCCGAGAATACGAAGCTGAATTGGAGGCTCAGCTGCAGCAGATTGAAACCAGGAACCGGGACCTCTTGTCAGAGAATAACCGCCTTCGCATGGAGCTGGAGTCTGTGAAG

Seq C2 exon

AGCCACAATCATGTCCCTGGAAGACTTTGAGCAGCGTTTGAATCAAGCCATTGAAAGAAATGCCTTCCTAGAGAGTGAGCTGGATGAGAAGGAGAATCTTCTAGAATCTGTGCAGAGGCTGAAGGATGAAGCCCGAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSMUSG00000022678_MULTIEX1-1/5=C1-4

Average complexity

C3

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.810 A=0.840 C2=0.478

Domain overlap (PFAM):

C1:

PF079267=TPR_MLP1_2=PU(30.0=85.7),PF040127=PspA_IM30=PU(11.6=28.6),PF088265=DMPK_coil=PU(5.3=10.7)

A:

PF079267=TPR_MLP1_2=FE(63.8=100),PF040127=PspA_IM30=FE(73.9=100),PF088265=DMPK_coil=FE(89.5=100),PF0017016=bZIP_1=PU(89.4=80.8),PF075586=Shugoshin_N=WD(100=55.8)

C2:

PF079267=TPR_MLP1_2=PD(3.8=30.0),PF040127=PspA_IM30=PD(11.6=80.0),PF088265=DMPK_coil=PD(1.8=10.0),PF0017016=bZIP_1=PD(6.4=30.0)

Main Inclusion Isoform:

ENSMUSP00000118005