HsaEX6001728 @ hg38
Exon Skipping
Gene
ENSG00000180210 | F2
Description
coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535]
Coordinates
chr11:46728664-46739118:+
Coord C1 exon
chr11:46728664-46728837
Coord A exon
chr11:46729380-46729561
Coord C2 exon
chr11:46739048-46739118
Length
182 bp
Sequences
Splice sites
3' ss Seq
CCCTTCTTCCTTCCCCAAAGCTT
3' ss Score
9.1
5' ss Seq
CTGGCAAGT
5' ss Score
2.89
Exon sequences
Seq C1 exon
GTACGAGCGAAACATTGAAAAGATATCCATGTTGGAAAAGATCTACATCCACCCCAGGTACAACTGGCGGGAGAACCTGGACCGGGACATTGCCCTGATGAAGCTGAAGAAGCCTGTTGCCTTCAGTGACTACATTCACCCTGTGTGTCTGCCCGACAGGGAGACGGCAGCCAG
Seq A exon
CTTGCTCCAGGCTGGATACAAGGGGCGGGTGACAGGCTGGGGCAACCTGAAGGAGACGTGGACAGCCAACGTTGGTAAGGGGCAGCCCAGTGTCCTGCAGGTGGTGAACCTGCCCATTGTGGAGCGGCCGGTCTGCAAGGACTCCACCCGGATCCGCATCACTGACAACATGTTCTGTGCTG
Seq C2 exon
GTTACAAGCCTGATGAAGGGAAACGAGGGGATGCCTGTGAAGGTGACAGTGGGGGACCCTTTGTCATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000180210_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.188
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(20.9=100),PF0008921=Trypsin=PU(1.6=10.0)
A:
PF0008921=Trypsin=PD(2.2=3.2),PF0008921=Trypsin=FE(48.8=100)
C2:
PF0008921=Trypsin=FE(18.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAGCGAAACATTGAAAAGAT
R:
CTTCATGACAAAGGGTCCCCC
Band lengths:
243-425
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains