HsaEX6006556 @ hg19
Exon Skipping
Gene
ENSG00000160255 | ITGB2
Description
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) [Source:HGNC Symbol;Acc:6155]
Coordinates
chr21:46326830-46330700:-
Coord C1 exon
chr21:46330640-46330700
Coord A exon
chr21:46330199-46330287
Coord C2 exon
chr21:46326830-46327010
Length
89 bp
Sequences
Splice sites
3' ss Seq
CAGCCGGCCTCGTCCCTCAGTCC
3' ss Score
5.18
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
Exon sequences
Seq C1 exon
GACATGCTGGGCCTGCGCCCCCCACTGCTCGCCCTGGTGGGGCTGCTCTCCCTCGGGTGCG
Seq A exon
TCCTCTCTCAGGAGTGCACGAAGTTCAAGGTCAGCAGCTGCCGGGAATGCATCGAGTCGGGGCCCGGCTGCACCTGGTGCCAGAAGCTG
Seq C2 exon
AACTTCACAGGGCCGGGGGATCCTGACTCCATTCGCTGCGACACCCGGCCACAGCTGCTCATGAGGGGCTGTGCGGCTGACGACATCATGGACCCCACAAGCCTCGCTGAAACCCAGGAAGACCACAATGGGGGCCAGAAGCAGCTGTCCCCACAAAAAGTGACGCTTTACCTGCGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255-'7-26,'7-23,10-26=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.027 C2=0.313
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(3.2=5.0)
A:
PF0143720=PSI=PU(83.3=83.3),PF0036213=Integrin_beta=PU(35.4=56.7)
C2:
PF0036213=Integrin_beta=FE(75.9=100),PF0036213=Integrin_beta=PU(3.1=14.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGGCTGCTCTCCCTC
R:
TTTTGTGGGGACAGCTGCTTC
Band lengths:
183-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)