HsaEX6006556 @ hg38
Exon Skipping
Gene
ENSG00000160255 | ITGB2
Description
integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]
Coordinates
chr21:44906915-44910785:-
Coord C1 exon
chr21:44910725-44910785
Coord A exon
chr21:44910284-44910372
Coord C2 exon
chr21:44906915-44907095
Length
89 bp
Sequences
Splice sites
3' ss Seq
CAGCCGGCCTCGTCCCTCAGTCC
3' ss Score
5.18
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
Exon sequences
Seq C1 exon
GACATGCTGGGCCTGCGCCCCCCACTGCTCGCCCTGGTGGGGCTGCTCTCCCTCGGGTGCG
Seq A exon
TCCTCTCTCAGGAGTGCACGAAGTTCAAGGTCAGCAGCTGCCGGGAATGCATCGAGTCGGGGCCCGGCTGCACCTGGTGCCAGAAGCTG
Seq C2 exon
AACTTCACAGGGCCGGGGGATCCTGACTCCATTCGCTGCGACACCCGGCCACAGCTGCTCATGAGGGGCTGTGCGGCTGACGACATCATGGACCCCACAAGCCTCGCTGAAACCCAGGAAGACCACAATGGGGGCCAGAAGCAGCTGTCCCCACAAAAAGTGACGCTTTACCTGCGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255-'7-33,'7-30,10-33
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.024 C2=0.332
Domain overlap (PFAM):
C1:
NO
A:
PF0143720=PSI=PU(83.3=83.3),PF0036213=Integrin_beta=PU(35.4=56.7)
C2:
PF0036213=Integrin_beta=FE(75.9=100),PF0036213=Integrin_beta=PU(3.1=14.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGGCTGCTCTCCCTC
R:
TTTTGTGGGGACAGCTGCTTC
Band lengths:
183-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains