MmuEX0024665 @ mm10
Exon Skipping
Gene
ENSMUSG00000000290 | Itgb2
Description
integrin beta 2 [Source:MGI Symbol;Acc:MGI:96611]
Coordinates
chr10:77541966-77546193:+
Coord C1 exon
chr10:77541966-77542026
Coord A exon
chr10:77542398-77542486
Coord C2 exon
chr10:77546000-77546193
Length
89 bp
Sequences
Splice sites
3' ss Seq
AGCCCTGTCTGTCTCCCCAGCTG
3' ss Score
9.52
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
GACATGCTGGGCCCACACTCACTGCTGCTTGCCCTAGCTGGACTGTTCTTCCTGGGATCTG
Seq A exon
CTGTGTCCCAGGAATGCACCAAGTACAAAGTCAGCAGTTGCCGGGACTGTATCCAGTCGGGGCCTGGCTGTTCCTGGTGCCAGAAGCTG
Seq C2 exon
ATCCCTCCTCTAGAACTTCACTGGACCAGGAGAACCTGACTCCTTGCGCTGTGACACACGGGCACAGCTGCTGCTGAAGGGTTGTCCAGCCGATGATATCATGGACCCCAGGAGCATCGCTAATCCTGAGTTCGACCAACGGGGGCAACGGAAACAGCTATCTCCACAAAAAGTGACACTTTACTTGCGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000290_MULTIEX1-2/2=1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.323
Domain overlap (PFAM):
C1:
NO
A:
PF0036213=Integrin_beta=PU(4.1=56.7)
C2:
PF0036213=Integrin_beta=PU(22.7=90.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCTAGCTGGACTGTTCTT
R:
CCGTTGGTCGAACTCAGGATT
Band lengths:
174-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types