HsaEX6007216 @ hg19
Exon Skipping
Gene
ENSG00000006747 | SCIN
Description
scinderin [Source:HGNC Symbol;Acc:21695]
Coordinates
chr7:12617167-12620846:+
Coord C1 exon
chr7:12617167-12617384
Coord A exon
chr7:12617689-12617843
Coord C2 exon
chr7:12620685-12620846
Length
155 bp
Sequences
Splice sites
3' ss Seq
GCTGTTGTTCACTGTTTTAGGAA
3' ss Score
10.13
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
Exon sequences
Seq C1 exon
GAATTGGAAAAAGCAGAAACAAAAACAGGCCGGGCATGGTGGCTCATACCTGTAATCCCCAACAATTTAGGAGGCCAAAGCCAGAGGACTGCTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCAACATATGGAGACCTTTTCCCTACAAAACACTTTTTTGAGAATTAGCAAAGCATGGTGGCACGCACCTGTAGTCCAAGCTGCTTGTGAGACTGAG
Seq A exon
GAAAGGAGTGTTCCCAGGATGAAAGCACAGCTGCTGCCATCTTCACTGTTCAGATGGATGACTATTTGGGTGGCAAGCCAGTGCAGAATAGAGAACTTCAAGGATATGAGTCTAATGACTTTGTTAGCTATTTCAAAGGCGGTCTGAAATACAAG
Seq C2 exon
GCTGGAGGCGTGGCATCTGGATTAAATCATGTTCTTACGAACGACCTGACAGCCAAGAGGCTCCTACATGTGAAGGGTCGTAGAGTGGTGAGAGCCACAGAAGTTCCCCTTAGCTGGGACAGTTTCAACAAGGGTGACTGCTTCATCATTGACCTTGGCACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000006747-'2-3,'2-2,4-3=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.722 A=0.005 C2=0.000
Domain overlap (PFAM):
C1:
PF0062617=Gelsolin=PD(40.0=75.7)
A:
PF0062617=Gelsolin=PD(49.4=78.8)
C2:
PF0062617=Gelsolin=PU(34.2=48.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTGAGGCCAGGAGTTTGAG
R:
GCTAAGGGGAACTTCTGTGGC
Band lengths:
242-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)