HsaEX6016882 @ hg38
Exon Skipping
Gene
ENSG00000079156 | OSBPL6
Description
oxysterol binding protein like 6 [Source:HGNC Symbol;Acc:HGNC:16388]
Coordinates
chr2:178361682-178387139:+
Coord C1 exon
chr2:178361682-178361815
Coord A exon
chr2:178373890-178374027
Coord C2 exon
chr2:178387061-178387139
Length
138 bp
Sequences
Splice sites
3' ss Seq
TATGCTTCTGTCTTCTGCAGGCT
3' ss Score
11.94
5' ss Seq
GAGGTATGT
5' ss Score
9.81
Exon sequences
Seq C1 exon
TGCATTCTCTTTTGAAGTCTGCATTTAATAGCATAGCTATAGAGAAGGAGAAGCTGAAGCAGATGGTTTCCGAGCAGGATCACAGTAAAGGCCACAGCACGCAGATGGCACGGCTCCGACAGTCACTGTCTCAG
Seq A exon
GCTGGTGAGCAAATCCATGTCAGTCTCCCCTTATCACAGCAAGTAGCCAATGAGAGCCGCCTCTCCATGTCAGAGTCTGTTTCTGAGTTCTTTGATGCCCAAGAGGTGCTCCTCTCTGCAAGTTCGTCAGAGAATGAG
Seq C2 exon
ATATCAGATGGAAAAACAAGTTCTGGGGGAAGTCGATGGAAATCCTGCCTGTTGGAACACTGAATGTCATGCTTCCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079156_MULTIEX2-2/11=C1-7
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.519 A=0.227 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0123713=Oxysterol_BP=FE(7.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCATTCTCTTTTGAAGTCTGCA
R:
GGAAGCATGACATTCAGTGTTCC
Band lengths:
210-348
Functional annotations
There are 2 annotated functions for this event
PMID: 15212954
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: glutathione s tranferase tag, pull down. ELM ID: ELMI001272; ELM sequence: ESVSEFFDAQE; Overlap: FULL
PMID: 17804640
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: cross linking study, detection by mass spectrometry. ELM ID: ELMI001272; ELM sequence: ESVSEFFDAQE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains