HsaEX6032484 @ hg19
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav 3 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12659]
Coordinates
chr1:108247172-108291699:-
Coord C1 exon
chr1:108291590-108291699
Coord A exon
chr1:108247582-108247683
Coord C2 exon
chr1:108247172-108247272
Length
102 bp
Sequences
Splice sites
3' ss Seq
TATTTTTTTCCTTTTTTTAGGTC
3' ss Score
12.58
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
TGGTCTTATGGCTTCTACCTCATCCATACCCAAGGACAAAATGGGTTAGAATTTTATTGCAAAACAAAAGATTTAAAGAAGAAATGGCTAGAACAGTTTGAAATGGCTTT
Seq A exon
GTCTAACATAAGACCAGACTATGCAGACTCCAATTTCCACGACTTCAAGATGCATACCTTCACTCGAGTCACATCCTGCAAAGTCTGCCAGATGCTCCTGAG
Seq C2 exon
GGGAACATTTTATCAAGGCTATTTATGTTTTAAGTGTGGAGCGAGAGCACACAAAGAATGTTTGGGAAGAGTAGACAATTGTGGCAGAGTTAATTCTGGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215-'17-19,'17-18,19-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(35.6=100),PF0063014=Filamin=PU(10.5=70.3)
A:
PF0016924=PH=PD(1.0=2.9),PF0013017=C1_1=PU(39.6=60.0),PF144461=Prok-RING_1=PU(25.9=40.0),PF0063014=Filamin=FE(10.8=100)
C2:
PF0013017=C1_1=PD(58.5=88.6),PF144461=Prok-RING_1=FE(63.0=100),PF0063014=Filamin=FE(10.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTCTTATGGCTTCTACCTCA
R:
CACCAGAATTAACTCTGCCACA
Band lengths:
211-313
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)