HsaEX6032484 @ hg38
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:12659]
Coordinates
chr1:107704550-107749077:-
Coord C1 exon
chr1:107748968-107749077
Coord A exon
chr1:107704960-107705061
Coord C2 exon
chr1:107704550-107704650
Length
102 bp
Sequences
Splice sites
3' ss Seq
TATTTTTTTCCTTTTTTTAGGTC
3' ss Score
12.58
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
TGGTCTTATGGCTTCTACCTCATCCATACCCAAGGACAAAATGGGTTAGAATTTTATTGCAAAACAAAAGATTTAAAGAAGAAATGGCTAGAACAGTTTGAAATGGCTTT
Seq A exon
GTCTAACATAAGACCAGACTATGCAGACTCCAATTTCCACGACTTCAAGATGCATACCTTCACTCGAGTCACATCCTGCAAAGTCTGCCAGATGCTCCTGAG
Seq C2 exon
GGGAACATTTTATCAAGGCTATTTATGTTTTAAGTGTGGAGCGAGAGCACACAAAGAATGTTTGGGAAGAGTAGACAATTGTGGCAGAGTTAATTCTGGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215-'45-44,'45-43,52-44=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(35.6=100),PF0063014=Filamin=PU(10.5=70.3)
A:
PF0016924=PH=PD(1.0=2.9),PF0063014=Filamin=FE(10.8=100),PF0013017=C1_1=PU(39.6=60.0)
C2:
PF0063014=Filamin=FE(10.8=100),PF0013017=C1_1=PD(58.5=88.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTCTTATGGCTTCTACCTCA
R:
CACCAGAATTAACTCTGCCACA
Band lengths:
211-313
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains