HsaEX6063743 @ hg19
Exon Skipping
Gene
ENSG00000148300 | REXO4
Description
REX4, RNA exonuclease 4 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:12820]
Coordinates
chr9:136273892-136277612:-
Coord C1 exon
chr9:136277419-136277612
Coord A exon
chr9:136276105-136276193
Coord C2 exon
chr9:136273892-136273966
Length
89 bp
Sequences
Splice sites
3' ss Seq
TCTTTGTGTTGATTTTCCAGGAG
3' ss Score
9.49
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
CCTGACAAGAGCCTTAGCCTTGGACTGTGAGATGGTGGGCGTGGGCCCTAAGGGGGAGGAGAGCATGGCCGCCCGTGTGTCCATCGTGAACCAGTATGGGAAGTGCGTTTATGACAAGTACGTCAAACCAACTGAGCCCGTGACGGACTATAGGACAGCGGTCAGTGGGATTCGGCCTGAGAACCTCAAGCAGG
Seq A exon
GAGAAGAGCTTGAAGTTGTTCAGAAGGAAGTGGCAGAGATGCTGAAGGGCAGAATTCTAGTGGGGCACGCTCTGCATAATGACCTAAAG
Seq C2 exon
GTACTATTTCTTGATCATCCAAAAAAGAAGATTCGGGACACACAGAAATATAAACCTTTCAAGAGTCAAGTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148300-'5-6,'5-5,7-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.109 A=0.150 C2=0.387
Domain overlap (PFAM):
C1:
PF0092919=RNase_T=PU(39.7=90.9)
A:
PF0092919=RNase_T=FE(25.4=100)
C2:
PF0092919=RNase_T=FE(21.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGTGTCCATCGTGAACCAG
R:
TCTGTGTGTCCCGAATCTTCT
Band lengths:
167-256
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)