HsaEX6064270 @ hg19
Exon Skipping
Gene
ENSG00000188986 | COBRA1
Description
cofactor of BRCA1 [Source:HGNC Symbol;Acc:24324]
Coordinates
chr9:140166533-140167998:+
Coord C1 exon
chr9:140166533-140166674
Coord A exon
chr9:140166959-140167067
Coord C2 exon
chr9:140167234-140167998
Length
109 bp
Sequences
Splice sites
3' ss Seq
CCCTGCACGGCCTTTTCCAGGAA
3' ss Score
7.09
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
TGGAGACCTTTGGCGACTTGGCCTTTGGCGACATCTTCCTCCACCTGCTCACGGGCAACCTTGCGCTGCTGGCCGACGAATTTGCCCTTGAGGACTTCTGCAGCAGCCTCTTCGATGGCTTCTTCCTCACCGCCTCTCCAAG
Seq A exon
GAAGGAGAACGTGCACCGGCACGCGCTGCGGCTCCTCATTCACCTGCACCCCAGGGTGGCCCCGTCTAAGCTGGAGGCGTTGCAGAAGGCCCTGGAGCCTACAGGCCAG
Seq C2 exon
AGCGGAGAGGCAGTGAAGGAGCTTTACTCCCAGCTCGGCGAGAAGCTGGAACAGCTGGATCACCGGAAGCCCAGCCCGGCACAGGCTGCGGAGACGCCGGCCCTGGAGCTGCCCCTCCCCAGCGTGCCCGCCCCTGCCCCGCTCTGAGGGCCCTCCAGACCTGCTCGGGTGCTGGGGCCATGCCGAGTCGCGGCCCTGCTCAGCCGGAAGAGGCTCCCGGACCTGGATGTACAGGGCAGTCTCTCTTCCCGGGGCTATGGCTGGGCCTGTCCTGCCGTCATGGCCCCCTGCTTCCTGCTCCTTGGAGCTGGCTCCCGGACCTTGCCCACCATCCATGCAGTGGCTCCCAGGGCAGAGCCTCTCCTTGTACTTTGGCAGCCATAGAAAGCGTGCTCATTTTCTGTTTTCCTGTGTTAGGAAAAAACCACCTGTTTTCCAAGGGGAGAGGGCGGGGCCTGAGGGTGGGGGCGGGGCCTCTTCATTGGCCCAGCTTGGCGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986-'13-12,'13-11,14-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.162 C2=0.562
Domain overlap (PFAM):
C1:
PF062098=COBRA1=FE(9.9=100),PF069126=DUF1275=PD(78.6=91.7)
A:
PF062098=COBRA1=FE(7.6=100)
C2:
PF062098=COBRA1=PD(9.9=95.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCTTCCTCACCGCCTCTCC
R:
CTGTACATCCAGGTCCGGGAG
Band lengths:
258-367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)