HsaEX6079185 @ hg19
Exon Skipping
Gene
ENSG00000101204 | CHRNA4
Description
cholinergic receptor, nicotinic, alpha 4 (neuronal) [Source:HGNC Symbol;Acc:1958]
Coordinates
chr20:61987723-61992656:-
Coord C1 exon
chr20:61992529-61992656
Coord A exon
chr20:61990900-61991051
Coord C2 exon
chr20:61987723-61987767
Length
152 bp
Sequences
Splice sites
3' ss Seq
TGGCCTGCCTCTCCCCGCAGCCA
3' ss Score
11.58
5' ss Seq
GTGGTAGGT
5' ss Score
7.23
Exon sequences
Seq C1 exon
CCACAGGAGAAGACGAACCGGGCCCGGCGGCCGAAGCGGCCCGCGAGGCGCGGGAGGCATGAAGTTGGGCGCGCACGGGCCTCGAAGCGGCGGGGAGCCGGGAGCCGCCCGCATCTAGAGCCCGCGAG
Seq A exon
CCAGCAGCCATGTGGAGACCCGGGCCCACGCCGAGGAGCGGCTCCTGAAGAAACTCTTCTCCGGTTACAACAAGTGGTCCCGACCCGTGGCCAACATCTCGGACGTGGTCCTCGTCCGCTTCGGCCTGTCCATCGCTCAGCTCATTGACGTG
Seq C2 exon
GATGAGAAGAACCAGATGATGACCACGAACGTATGGGTGAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101204-'7-10,'7-9,9-10=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.029 C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
PF0293118=Neur_chan_LBD=PU(18.8=76.5)
C2:
PF0293118=Neur_chan_LBD=FE(15.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGGAGAAGACGAACCGGG
R:
TGCTTCACCCATACGTTCGTG
Band lengths:
170-322
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)