HsaEX6086591 @ hg19

Exon Skipping

Gene

ENSG00000171557 | FGG

Description

fibrinogen gamma chain [Source:HGNC Symbol;Acc:3694]

Coordinates

chr4:155531219-155533353:-

Coord C1 exon

chr4:155533170-155533353

Coord A exon

chr4:155532957-155533050

Coord C2 exon

chr4:155531219-155531349

Length

94 bp

Sequences

Splice sites

3' ss Seq

TCTCTGATCCTATATTACAGATA

3' ss Score

8.84

5' ss Seq

TCGGTAAGG

5' ss Score

10.48

Exon sequences

Seq C1 exon

GGTAGTTATTGTCCAACTACCTGTGGCATTGCAGATTTCCTGTCTACTTATCAAACCAAAGTAGACAAGGATCTACAGTCTTTGGAAGACATCTTACATCAAGTTGAAAACAAAACATCAGAAGTCAAACAGCTGATAAAAGCAATCCAACTCACTTATAATCCTGATGAATCATCAAAACCAA

Seq A exon

ATATGATAGACGCTGCTACTTTGAAGTCCAGGAAAATGTTAGAAGAAATTATGAAATATGAAGCATCGATTTTAACACATGACTCAAGTATTCG

Seq C2 exon

ATATTTGCAGGAAATATATAATTCAAATAATCAAAAGATTGTTAACCTGAAAGAGAAGGTAGCCCAGCTTGAAGCACAGTGCCAGGAACCTTGCAAAGACACGGTGCAAATCCATGATATCACTGGGAAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000171557-'4-12,'4-11,7-12=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.001 A=0.045 C2=0.000

Domain overlap (PFAM):

C1:

PF045827=Reo_sigmaC=FE(38.4=100),PF087025=Fib_alpha=FE(42.1=100),PF083176=Spc7=PU(33.3=85.5)

A:

PF087025=Fib_alpha=PU(42.9=96.8),PF083176=Spc7=PU(27.4=93.5),PF123293=TMF_DNA_bd=PU(40.4=67.7),PF032468=Pneumo_ncap=PU(30.0=96.8),PF125843=TRAPPC10=PU(12.4=41.9)

C2:

PF087025=Fib_alpha=PD(55.7=86.7),PF083176=Spc7=FE(41.5=100),PF123293=TMF_DNA_bd=PD(57.7=66.7),PF032468=Pneumo_ncap=FE(44.0=100),PF125843=TRAPPC10=FE(41.9=100),PF0014713=Fibrinogen_C=PU(5.8=6.7)

Main Inclusion Isoform:

ENSP00000384552