HsaEX6086591 @ hg38
Exon Skipping
Gene
ENSG00000171557 | FGG
Description
fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694]
Coordinates
chr4:154610067-154612201:-
Coord C1 exon
chr4:154612018-154612201
Coord A exon
chr4:154611805-154611898
Coord C2 exon
chr4:154610067-154610197
Length
94 bp
Sequences
Splice sites
3' ss Seq
TCTCTGATCCTATATTACAGATA
3' ss Score
8.84
5' ss Seq
TCGGTAAGG
5' ss Score
10.48
Exon sequences
Seq C1 exon
GGTAGTTATTGTCCAACTACCTGTGGCATTGCAGATTTCCTGTCTACTTATCAAACCAAAGTAGACAAGGATCTACAGTCTTTGGAAGACATCTTACATCAAGTTGAAAACAAAACATCAGAAGTCAAACAGCTGATAAAAGCAATCCAACTCACTTATAATCCTGATGAATCATCAAAACCAA
Seq A exon
ATATGATAGACGCTGCTACTTTGAAGTCCAGGAAAATGTTAGAAGAAATTATGAAATATGAAGCATCGATTTTAACACATGACTCAAGTATTCG
Seq C2 exon
ATATTTGCAGGAAATATATAATTCAAATAATCAAAAGATTGTTAACCTGAAAGAGAAGGTAGCCCAGCTTGAAGCACAGTGCCAGGAACCTTGCAAAGACACGGTGCAAATCCATGATATCACTGGGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000171557-'3-12,'3-11,6-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.021 C2=0.000
Domain overlap (PFAM):
C1:
PF045827=Reo_sigmaC=FE(38.4=100),PF087025=Fib_alpha=FE(42.1=100),PF083176=Spc7=PU(33.3=85.5)
A:
PF087025=Fib_alpha=PU(42.9=96.8),PF083176=Spc7=PU(27.6=93.5),PF123293=TMF_DNA_bd=PU(40.4=67.7)
C2:
PF045827=Reo_sigmaC=PD(24.5=86.7),PF087025=Fib_alpha=PD(26.9=86.7),PF083176=Spc7=FE(27.7=100),PF0014713=Fibrinogen_C=PU(1.2=6.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATCAGAAGTCAAACAGCTGA
R:
GGATTTGCACCGTGTCTTTGC
Band lengths:
183-277
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains