HsaEX6092358 @ hg38
Exon Skipping
Gene
ENSG00000141968 | VAV1
Description
vav guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:12657]
Coordinates
chr19:6821791-6822514:+
Coord C1 exon
chr19:6821791-6821859
Coord A exon
chr19:6822221-6822329
Coord C2 exon
chr19:6822419-6822514
Length
109 bp
Sequences
Splice sites
3' ss Seq
CCTGACCTCACAACCCACAGCGA
3' ss Score
5.8
5' ss Seq
CCGGTGCGT
5' ss Score
9.74
Exon sequences
Seq C1 exon
GCCCTTCCCCACCGAGGAGGAGAGTGTAGGTGATGAAGACATCTACAGTGGCCTGTCCGACCAGATCGA
Seq A exon
CGACACGGTGGAGGAGGATGAGGACCTGTATGACTGCGTGGAGAATGAGGAGGCGGAAGGCGACGAGATCTATGAGGACCTCATGCGCTCGGAGCCCGTGTCCATGCCG
Seq C2 exon
CCCAAGATGACAGAGTATGACAAGCGCTGCTGCTGCCTGCGGGAGATCCAGCAGACGGAGGAGAAGTACACTGACACGCTGGGCTCCATCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141968-'10-11,'10-10,11-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.367 A=0.286 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0062115=RhoGEF=PU(8.3=37.8)
C2:
PF0062115=RhoGEF=PU(11.4=62.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCACCGAGGAGGAGAGTGTAG
R:
CTGGATGGAGCCCAGCGT
Band lengths:
154-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains